针刺联合聚肌胞注射液和更昔洛韦眼用凝胶治疗眼部带状疱疹Clinical Observation of Acupuncture Therapy Combined with Polyinosinic-polycytidylic Acid Injection and Ganciclovir Ophthalmic Gel on Ocular Herpes Zoster
鲁勃文,明春平,杨忠友,孙欣
LU Bowen,MING Chunping,YANG Zhongyou,SUN Xin
摘要(Abstract):
目的:探讨针刺联合聚肌胞注射液和更昔洛韦眼用凝胶在眼部带状疱疹患者中的治疗效果。方法:从收治的眼部带状疱疹患者中随机抽取100例作为研究对象,按照随机数字表法将其分为研究组和对照组,每组各50例;对照组给予聚肌胞注射液和更昔洛韦眼用凝胶治疗,研究组在对照组治疗的基础上加以针刺治疗,比较两组治疗效果,观察两组患者治疗后各项临床症状消失时间及不良反应情况。结果:研究组总体有效率(92.00%)明显高于对照组(78.00%),差异有统计学意义(P<0.05);研究组疼痛消失时间、眼部损害消失时间、皮疹消褪时间及虹膜睫状体炎消失的时间均明显低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率相比较,差异无统计学意义(P>0.05)。结论:针刺联合聚肌胞注射液和更昔洛韦眼用凝胶治疗眼部带状疱疹,效果明显,值得推广。
Objective: To explore the curative effect of acupuncture combined with polyinosinic-polycytidylic acid injection and ganciclovir ophthalmic gel in patients with ocular herpes zoster. Methods:One hundred patients with ocular herpes zoster were randomly divided into control group and research group. The control group was treated with ganciclovir ophthalmic gel and polyinosinic-polycytidylic acid injection,while the research group received additional therapy of acupuncture. The curative effects of the two groups were compared after the treatment. Results: The total effective rate of research group(92. 00%) was higher than that of the control group(78. 00%)( P < 0. 05),while the time for pain,ophthalmic injury,rash and iridocyclitis disappearing in the research group was shorter than that of the control group( P < 0. 05). There was on significant difference between the two groups in incidence of adverse reactions( P > 0. 05). Conclusion: Acupuncture combined with polyinosinicpolycytidylic acid and ganciclovir ophthalmic gel in the treatment of ocular herpes zoster can get ideal effects and it is worthy of promotion.
关键词(KeyWords):
针刺疗法;聚肌胞苷酸;更昔洛韦;带状疱疹;眼
acupuncture therapy;polyinosinic-polycytidylic acid;ganciclovir;herpes zoster;eye
基金项目(Foundation):
作者(Author):
鲁勃文,明春平,杨忠友,孙欣
LU Bowen,MING Chunping,YANG Zhongyou,SUN Xin
DOI: 10.19367/j.cnki.1000-2707.2015.08.028
参考文献(References):
- [1]宋桂莲,刘怀栋,刘平英,等.疱疹解毒方治疗眼部带状疱疹的临床疗效观察[J].河北中医药学报,2012(2):27-28+34.
- [2]赵红霞.32例中西医结合治疗眼部带状疱疹的临床研究[J].昆明医学院学报,2012(3):188-189.
- [3]谢清波.中西医结合治疗眼部带状疱疹34例临床观察[J].中医药导报,2013(1):56-57.
- [4]于希彦.更昔洛韦眼用凝胶和阿昔洛韦滴眼液治疗单疱病毒性角膜炎的疗效对比[J].中国现代药物应用,2013(13):130-131.
- [5]黎锦萍,周沛辉,郭娴吟.更昔洛韦眼用凝胶在单纯疱疹病毒性角膜炎中应用的效果观察[J].临床医学工程,2013(3):306-307.
- [6]王光超.皮肤性病学[M].3版.北京:人民卫生出版社,1996.87-88.
- [7]Yoshida I,Azuma M.An alternative receptor to poly I:C on cell surfaces for interferon induction[J].Microbiol Immunol,2013(5):329-333.
- [8]Murray C,GriffinéW,O'Loughlin E,et al.Interdependent and independent roles of type I interferons and IL-6in innate immune,neuroinflammatory and sickness behaviour responses to systemic poly I:C[J].Brain Behav Immun,2015,pii:S0889-1591(15)00114-2.
- [9]Wang PH,Weng SP,He JG.Nucleic acid-induced antiviral immunity in invertebrates:an evolutionary perspective[J].Dev Comp Immunol,2015(2):291-296.
- [10]许婷.眼部带状疱疹采用阿昔洛韦联合龙胆泻肝汤治疗的效果观察[J].中国卫生产业,2014(2):159-160.
- [11]李建萍,赵英侠,陈坚.针刺与应激免疫关系的实验研究.针刺研究,2000(2):104-105.
文章评论(Comment):
|
||||||||||||||||||
|
||||||||||||||||||