曾伟英,何庭宇,卢兰芬,梁智恒
ZENG Weiying1,HE Tingyu2,LU Lanfen2,LIANG Zhiheng2(1.Department of Neurology

• 1:中山市人民医院神经内科
• 2:中山市人民医院检验中心

摘要(Abstract)：

目的:探讨不同年龄、性别体检人群血液流变学特性与肝肾功能、血脂、血糖之间的关系。方法:对960例门诊和保健科体检人群按年龄、性别分4组同时检测外周血中血脂、血糖、肝肾功能与血液流变学指标。结果:血液流变学特性与生化指标改变有着明显相关性,不同年龄男、女性体检者的共同点是胆固醇(GHOL)、甘油三脂(TRIG)、高密度脂蛋白胆固醇(LDL-ch)、血糖(BS)、尿素氮(BUN)、肌酐(CREAT)、尿酸(UA)、总蛋白(TP)、球蛋白(GLB)与全血粘度,CREAT、TP、GLB与血浆粘度,LDL-ch、BS、丙氨酸氯基转移酶(ALT)、TP、GLB、碱性磷酸酶(ALP)与血沉、血沉方程K值呈直线正相关,HDL-ch、白蛋白/球蛋白(A/G)、ALB与血液流变学各指标呈负相关,ALT、ALS与全血还原粘度、血沉、血沉方程K值有相关性,且在50岁以上人群表现更明显,男性比女性明显。结论:血液流变学特性改变受到血糖、血脂、肝肾功能的影响并与性别、年龄增长有密切关系。
Objective:To study the relation of hemorrheological features with serum fat,serum sugar,hepatic function,and kidney function of people taking health examination in different age and sex groups.Methods: Nine hundred and sixty people selected from out-patient clinic and health examination service were divided into four groups according to age and sex,and their serum fat,serum sugar,hepatic function,kidney function and hemorrheology were measured and analyzed.Results: There were significant correlations between hemorrheological features and biochemistry index changes,specially in males and in people above 50 years old.There were positive correlations between GHOL,TRIG,LDL-ch,BS,BUN,CREAT,UA,TP,GLB and whole blood viscosity,between CREAT,TP,GLB and serum viscosity,and between LDL-ch,BS,ALT,TP,GLB,AKP and ESR and erythrocyte sedimentati on equational coeffient K.There were negative correlations between HDL-ch,A/G,ALB and hemorrheology.There were some correlation between ALT,ALS and whole blood restore viscosity,ESR,erythrocyte sedimentati on equational coeffient K.Conclusions: Hemorrheology change is influenced by serum fat,serum sugar,hepatic function,kidney function and closely relates to age and sex.

关键词(KeyWords)： 年龄因素;性别因素;血液流变学;肝功能试验;肾功能试验
age factors;sex factors;hemorheology;liver function tests;kidney function tests

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 曾伟英,何庭宇,卢兰芬,梁智恒
ZENG Weiying1,HE Tingyu2,LU Lanfen2,LIANG Zhiheng2(1.Department of Neurology

DOI: 10.19367/j.cnki.1000-2707.2009.01.015

参考文献(References)：

• [1]何庭宇,杜宜,何结冰,等.红细胞免疫黏附功能和血液流变学特性与脑血管病的相关性[J].复旦学报(医学科学版),2001(5):400-403.
• [2]泰任甲.临床血液流变学[M].北京:北京大学医学出版社,2003:112-113.
• [3]来锦,胡桂才,张凤霞,等.不同职业群体的血液流变性调查分析[J].中国微循环,2007(1):55-57.
• [4]杨素新.老年人增龄与肾功能关系[J].辽宁医学杂志,2001(1):37-38.
• [5]张晓英,牟善初,余霞君,等.5 606例老年人肾功能测定及正常值研究[J].中国老年学杂志,1994(6):346-349.
• [6]田牛,修瑞娟,邹荫方.微循环障碍相关疾病[M].郑州:河南科学技术出版社,1985:302-303.

文章评论(Comment)：