贵州医科大学学报

2017, v.42;No.203(08) 987-990

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大肠癌患者生存质量与疾病症状及心理状态的相关性分析
Correlation Analysis between Quality of Life and Disease Symptoms together with Psychological Status of Patients with Colorectal Cancer

王秀英;
WANG Xiuying;Department of General Surgery,Center Hospital of Tongchuan Mining Bureau;

摘要(Abstract):

目的:探讨大肠癌患者疾病症状、心理情况与生存质量的相关性。方法:采用生存质量测定量表简表(WHOQOL-BREF)、医院焦虑抑郁量表(HADS)对216例大肠癌患者的生存质量水平、焦虑抑郁情况和疾病症状进行问卷调查,分析患者心理状态、临床症状对其生存质量水平的影响,Logistic回归分析大肠癌患者生存质量的影响因素。结果:收回合格问卷204份,有腹痛、腹胀、转移瘤症状、营养不良症状的大肠癌患者生理领域、心理领域得分和生存质量总体得分较无上述症状的患者明显下降,差异有统计学意义(P<0.05);有焦虑和抑郁症状的大肠癌患者生理领域、心理领域、社会领域、环境领域和生存质量总体得分较无上述症状的患者明显下降,差异有统计学意义(P<0.05);腹痛、腹胀、转移、营养不良、焦虑和抑郁与大肠癌患者生存质量总分之间呈明显负相关。结论:大肠癌患者的生存质量与患者疾病症状和心理状况密切相关,通过减轻患者疾病症状,加强心理疏导,可改善患者的整体生存质量水平。
Objective: To investigate the correlation between the symptoms,psychological status and quality of life of patients with colorectal cancer. Methods: Adopting WHOQOL-BREF and HADS to investigate level of quality of life,anxiety and depression conditions,and symptoms of the disease over 216 cases of colorectal cancer; analyzing the influence of psychological status and clinical symptoms on quality of life. Logistic regression analysis was adopted to analyze the influencing factors of quality of life of patients. Results: 204 questionnaires were collected; physical and psychological score and quality of life overall score of colorectal cancer patients with abdominal pain,abdominal distension,metastasis and malnutrition were significantly lower than the patients without these symptoms,the differences were statistically significant( P < 0. 05). Physical,psychological,social,environmental and quality of life overall score of colorectal cancer patients with anxiety and depression were significantly lower than the patients without the above symptoms,the differences were statistically significant( P < 0. 05). Abdominal pain,distension,metastasis,malnutrition,anxiety and depression were negatively correlated with quality of life scores of patients with colorectal cancer. Conclusion: The quality of life in patients with colorectal cancer was closely related to the disease symptoms and psychological status. Reducing the disease symptoms and strengthening psychological care can improve the overall quality of life of patients.

关键词(KeyWords): 大肠癌;症状;焦虑;抑郁;生存质量
colorectal cancer;symptom;anxiety;depression;quality of life

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作者(Author): 王秀英;
WANG Xiuying;Department of General Surgery,Center Hospital of Tongchuan Mining Bureau;

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DOI: 10.19367/j.cnki.1000-2707.2017.08.27

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