王翠,王迪芬
WANG Cui,WANG Difen

• 1:贵州医科大学附属医院重症医学科

摘要(Abstract)：

目的:探讨持续脑电双频指数(BIS)监测在判断急性脑损伤昏迷患者预后中的应用价值。方法:43例ICU急性脑损伤昏迷患者,根据预后分为生存组(n=27)和死亡组(n=16),所有患者行持续BIS监测并计算BIS平均值,计算首个24 h急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分及BIS监测时Glascow昏迷评分(GCS),分析BIS值、GCS评分及APACHEⅡ评分的相关性及3者联合对判断急性脑损伤昏迷预后的价值。结果:除年龄外,死亡组APACHEⅡ评分明显高于生存组,BIS值、GCS评分明显低于生存组,差异有统计学意义(P<0.01);BIS值与GCS评分呈正相关(r=0.385,P=0.008),与APACHEⅡ评分呈负相关(r=-0.372,P=O.014)。结论:BIS联合APACHEⅡ评分、GCS评分可在早期判断急性脑损伤昏迷患者的预后。
Objective: To discuss the application value of continuous bispectral index( BIS) monitor in judging the prognosis of patients with acute brain injury coma. Methods: According to the prognosis,43 patients with acute brain injury admitted to ICU were divided into survival group( n = 27) and death group( n = 16). All patients underwent continuous BIS monitor. The mean values of BIS were calculated. At the same time,the acute physiology and chronic health evaluation II( APACHE II)score and Glascow Coma Scale score( GCS) were recorded. Differences in age,APACHE II score,GCS score and BIS values were compared between the two groups. The correlation between BIS and GCS score,APACHE II score were respectively analyzed,and the value of combining three indexes to judge prognosis was analyzed. Results: There was no significant difference in the age between two groups( P > 0. 05). APACH II score in death group was significantly higher than that in survival group( P < 0. 01) while BIS value and GCS in death group were significantly lower than those in survival group( P < 0. 01). BIS value was positively correlated with GCS( r = 0. 385,P = 0. 008) but was negatively correlated with APACHE II( r =-0. 372,P = O. 014). Conclusion: BIS combined with GCS score and APACHEⅡ score can judge the prognosis of patients with acute brain injury coma as early as possible.

关键词(KeyWords)： 脑电双频指数;重症监护病房;急性脑损伤;Glascow昏迷评分
bispectral index;intensive care unit;acute brain injury;Glascow coma score

Abstract:

Keywords:

基金项目(Foundation): 2011年国家临床重点专科建设项目[财社(2011)170号];; 2011年贵州省临床重点学科建设项目[黔卫办发(2011)52号]

作者(Author): 王翠,王迪芬
WANG Cui,WANG Difen

DOI: 10.19367/j.cnki.1000-2707.2015.07.019

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