贵州医科大学学报

2018, v.43;No.213(06) 738-741

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乳腺钼靶摄影联合超声弹性系统对乳腺癌的诊断价值
The Diagnostic Value of Breast Cancer by Breast Mammography and Ultrasound Elastic System,Monotherapy and Combined Therapy

魏云龙;刘剑桥;王晓春;
WEI Yunlong;LIU Jianqiao;WANG Xiaochun;School of Medicine of Hebei University;Department of Mammary Gland Surgery,the Affiliated Hospital of Hebei University;

摘要(Abstract):

目的:探讨乳腺钼靶摄影联合超声弹性系统对乳腺癌诊断的价值。方法:选择预手术乳腺肿块患者150例,依据随机原则均分成超声组、钼靶组和联合组,超声组行常规乳腺彩超加弹性系统检查,钼靶组行乳腺钼靶摄影检查,联合组行乳腺钼靶摄影联合常规彩超加弹性系统检查;比较各组乳腺肿块患者的弹性成像评分、钼靶级别,并与术后病理学诊断结果比较,评价3种检查方式对乳腺癌的诊断敏感性、诊断特异性及检出率。结果:超声组弹性评分≥3分患者20例、联合组22例,两组比较差异无统计学意义(P>0.05);钼靶组钼靶级别>3级患者14例、联合组18例,两组比较差异无统计学意义(P>0.05);经术后病理确诊为乳腺癌病例的超声组23例、钼靶组26例、联合组24例,3组比较差异无统计学意义(P>0.05);在3组检查中,联合组的诊断敏感性最高,且各组间比较具有统计学意义(P<0.05);但3种方法检查的特异性比较,差异无统计学意义(P>0.05);联合组对乳腺癌检出率最高、漏诊率最低,3种检查方法对乳腺癌的检出率及漏诊率比较差异具有统计学意义(P<0.05)。结论:术前采用超声弹性系统检查联合乳腺钼靶摄影检查对乳腺肿块的良恶性判断优于单一的超声弹性系统检查或乳腺钼靶摄影。
Objective: To explore the diagnostic value of combined mammography and ultrasound elastography in breast cancer. Methods: 150 patients with pre-operation breast masses were selected and randomly divided into the ultrasound group,the molybdenum target group and the combined group. The ultrasound group underwent routine breast ultrasound and elastic system examination.Mammography was performed in the mammography group. The combined group underwent mammography combined with routine color Doppler ultrasound and elastic system examination. The elastography scores and mammography level of breast masses were compared with those of postoperative pathological diagnosis. The diagnostic sensitivity,specificity and detection rate of three treatments for breast cancer were assessed. Results: The elasticity scores were more than 3 points in 20 cases in the ultrasound group and 22 cases in the combined group,and the difference was not statistically significant( P >0. 05). There was no significant difference in molybdenum target > grade 3 and 14 cases in the molybdenum target group and 18 in the combined group( P > 0. 05). Through postoperative pathology examination,23 cases in the ultrasound group,26 cases in molybdenum target group and 24 cases in combined group were diagnosed as patients with breast cancer,with no significant difference among the 3 groups( P > 0. 05). The diagnostic sensitivity of the combined group was the highest,and the difference among the 3 groups was statistically significant( P < 0. 05). But there was no significant difference in specificity among the 3 methods( P > 0. 05). In the 3 groups of breast masses,the combined group had the highest detection rate and the lowest missed diagnosis rate. There was a statistically significant difference in the detection rate and missed diagnosis rate between the 3 methods( P < 0. 05).Conclusion: Compared with monotherapy of doppler ultrasound elastography or mammography,the combined therapy has better clinical significance in the diagnosis of benign and malignant breast cancer. And it is worthy of clinical promotion.

关键词(KeyWords): 乳腺肿瘤;弹性成像技术;乳腺钼靶摄影;敏感性与特异性;诊断
breast cancer;ultrasonic elastography;mammography;diagnosis

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作者(Author): 魏云龙;刘剑桥;王晓春;
WEI Yunlong;LIU Jianqiao;WANG Xiaochun;School of Medicine of Hebei University;Department of Mammary Gland Surgery,the Affiliated Hospital of Hebei University;

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DOI: 10.19367/j.cnki.1000-2707.2018.06.026

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