贵州医科大学学报

2018, v.43;No.219(12) 1445-1447

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老年肺炎患者血清降钙素原、超敏C反应蛋白及D-二聚体水平的表达及意义
Expression of Serum Procalcitonin,Hypersensitive C-reactive Protein and D-dimer in Senile Pneumonia

马文;龙启忠;杨卉;张艳;胡全;
MA Wen;LONG Qizhong;YANG Hui;ZHANG Yan;HU Quan;General Ward,Affiliated Hospital of Guizhou Medical University;Respiratory and Critical Care Unit,Affiliated Hospital of Guizhou Medical University;

摘要(Abstract):

目的:探讨血清降钙素原(PCT)、超敏C反应蛋白(hs-CRP)及D-二聚体(D-Dimer)水平在老年肺炎中的表达及意义。方法:47例老年肺炎患者作为观察组,再根据CURB-65评分分为低危组(n=20)、中危组(n=15)及高危组(n=12),选取同期健康体检老年人20例作为对照组;分别于入院或体检时检测血清PCT、hsCRP及D-Dimer水平,分析不同程度老年肺炎患者病情与PCT、hs-CRP及D-Dimer的关系。结果:与对照组比较,观察组老年肺炎患者血清PCT、hs-CRP及D-Dimer水平显著升高,差异有统计学意义(P <0. 05); 3组老年肺炎患者血清PCT、hs-CRP及D-Dimer水平比较,高危组>中危组>低危组,差异有统计学意义(P <0. 05)。结论:血清PCT、hs-CRP及D-Dimer水平检测能用于老年肺炎病情危重程度的判断。
Objective: To investigate the expression and significance of serum procalcitonin( PCT),hypersensitive C-reactive protein( hs-CRP) and D-dimer in senile pneumonia. Methods: 47 elderly patients with pneumonia were divided into three groups according to CURB-65 score: low risk group( n= 20),moderate risk group( n = 15) and high risk group( n = 12). 20 healthy aged persons were selected as control group. The serum levels of PCT,hs-CRP and D-Dimer were measured at admission or physical examination,and the relationship between PCT,hs-CRP and D-Dimer in elderly patients with pneumonia of different degrees was analyzed. Results: Compared with the control group,the serum levels of PCT,hs-CRP and D-Dimer in the elderly patients with pneumonia in the observation group were significantly higher than those in the control group,and the difference was statistically significant( P < 0. 05). The levels of serum PCT,hs-CRP and D-Dimer levels among three groups of elderly patients with pneumonia were compared: high risk group > medium risk group > low risk group,and the difference was statistically significant( P < 0. 05). Conclusion: Serum PCT,hs-CRP and D-Dimer levels can be used to judge the severity of pneumonia in the elderly.

关键词(KeyWords): 老年人;肺炎;血清;降钙素原;超敏C反应蛋白;D-二聚体;诊断
elderly people;pneumonia;serum;procalcitonin;hypersensitive C-reactive protein;D-Dimer;diagnosis

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基金项目(Foundation): 贵州省科学技术厅科技合作计划项目[黔科合LH字(2015)729号]

作者(Author): 马文;龙启忠;杨卉;张艳;胡全;
MA Wen;LONG Qizhong;YANG Hui;ZHANG Yan;HU Quan;General Ward,Affiliated Hospital of Guizhou Medical University;Respiratory and Critical Care Unit,Affiliated Hospital of Guizhou Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2018.12.016

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