吴泽兰,戚德清
WU Zelan,QI Deqing

• 1:贵阳医学院附院心内科
• 2:贵阳医学院医学科学研究所

摘要(Abstract)：

目的:分析二尖瓣环钙化(MAC)与房颤(AF)及血小板平均体积(MPV)的关系。方法:收集95例MAC患者(MAC组)与104例非MAC患者(对照组)的临床资料,检测血常规、血生化,比较两组患者的一般资料及超声心动图结果,分析MAC与AF及MPV的关系。结果:MAC组AF发生率明显高于对照组,差异具有统计学意义(P<0.01),MAC与AF发生率呈正相关(r=0.295,P<0.01);MAC组MPV明显高于对照组,差异具有统计学意义(P<0.01),MAC与MPV呈正相关(r=0.360,P<0.01);Logistic回归分析显示,MAC分别与AF(OR=22.45,95%CI为13.49~37.36,P<0.001)及MPV(OR=1.82,95%CI为1.43~2.33,P<0.001)独立相关。结论:MAC患者由于血小板活化所致的血栓风险高,对MAC患者应重视对AF及MPV的监测。
Objective: To analyze the relationship of mitral annular calcification( MAC) with atrial fibrillation( AF) and mean platelet volume( MPV). Methods: Ninety-five patients with MAC served as study group,and 104 people without MAC were chosen as control group. Routine blood test and blood biochemical test were carried out,clinical data and echocardiogram findings of patients in the two groups were compared. The relationship of MAC with AF and MPV was analyzed. Results: The incidence of AF was significantly higher in patients with MAC than that in controls( P < 0. 01). MAC was positively correlated with AF( P < 0. 01,r = 0. 295). MPV was significantly larger in patients with MAC than that in controls( P < 0. 01). MAC was positively correlated with MPV( P < 0. 01,r =0. 360). MAC was independently associated with AF( OR = 22. 45,95% CI 13. 49 ~ 37. 36,P <0. 001),and MPV( OR = 1. 82,95% CI 1. 43 ~ 2. 33,P < 0. 001). Conclusion: MAC patients have high risk of thrombosis caused by platelet activation,attention should be paid to monitor AF and MPV in MAC patients.

关键词(KeyWords)： 二尖瓣环钙化;心房颤动;血小板平均体积;血栓形成;冠状动脉疾病
mitral annular calcification;atrial fibrillation;mean platelet volume;thrombosis;coronary disease

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 吴泽兰,戚德清
WU Zelan,QI Deqing

DOI: 10.19367/j.cnki.1000-2707.2015.01.023

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