贵州医科大学学报

2016, v.41;No.184(01) 77-80

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支架成形术治疗颅外段颈动脉狭窄
Clinical Effect of Endovascular Stenting on Extracranial Carotid Stenosis

贺涛;李兴;周石;宋杰;蒋天鹏;
HE Tao;LI Xing;ZHOU Shi;SONG Jie;JIANG Tianpeng;School of Medical Image,Guizhou Medical University;

摘要(Abstract):

目的:探讨支架成形术治疗颅外段颈动脉狭窄的临床疗效。方法:颅外段颈动脉狭窄患者97例,根据手术方式分为实验组(n=45)和对照组(n=52),实验组患者行颅外颈动脉狭窄颈动脉支架植入血管成形术,对照组采用药物治疗;比较两组患者治疗1月和12月时卒中再发率,治疗前、治疗后1周、1、3、6及12月患者神经功能缺损(NIHSS)评分和治疗前、治疗后12月患者Rankin修订量表(mRS)评分。结果:实验组患者在术后1月和12月卒中再发率低于对照组,差异有统计学意义(P<0.05),治疗前,2组患者NIHSS、mRS评分比较差异无统计学意义(P>0.05);而治疗后1周、1、3、6及12月实验组NIHSS评分低于对照组,差异具有统计学意义(P<0.05);治疗后12月实验组mRS评分低于对照组差异亦有统计学意义(P<0.05)。结论:颈动脉支架血管成形术治疗颅外段颈动脉狭窄效果优于单纯药物治疗。
Objective: To explore the clinical effect of endovascular stenting on extracranial carotid stenosis. Method: In this research,patients with extracranial carotid stenosis in our hospital were retrospectively analyzed. Patients with endovascular stenting were defined as experimental group( n = 45)while patients with drug treatment as control group( n = 52). The stroke recurrence rate 1 month and12 months after treatment were compared between experimental group and control group,and neural function defect scale( NIHSS) and modified Rankin scale( mRS) were compared between two groups before treatment,1 week after treatment,1 month after treatment,3 months after treatment,6 months after treatment and 12 months after treatment. Results: There were statistically significant differences in the stroke recurrence rate after 1 month and 12 months between two groups( P < 0. 05). There were statistically significant differences in NIHSS score between two groups 1 weeks,1 month,3 months,6months and 12 months after treatment( P < 0. 05). There were statistically significant differences in mRS score between two groups 12 months after treatment( P < 0. 05) Conclusion: Compared with simple drug treatment,carotid stent angioplasty can effectively cure the carotid stenosis,improve cerebral blood flow and reduce the incidence of stroke.

关键词(KeyWords): 支架成形术;颈动脉狭窄;药物疗法;治疗结果;神经功能缺损评分;Rankin修订量表评分
endovascular stenting;extracranial carotid stenosis;drug therapy;therapeutic outcome;neural function defect scale;modified Rankin scale

Abstract:

Keywords:

基金项目(Foundation): 贵州省优秀科技教育人才省长专项基金项目[黔省专合字(2007)75号]

作者(Author): 贺涛;李兴;周石;宋杰;蒋天鹏;
HE Tao;LI Xing;ZHOU Shi;SONG Jie;JIANG Tianpeng;School of Medical Image,Guizhou Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2016.01.022

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