于萍,唐光健,杨晓霞,许志高,徐建国,杨晓宏
YU Ping,TANG Guangjian,YANG Xiaoxia,XU Zhigao,XU Jianguo,YANG Xiaohong

• 1:大同市第三人民医院医学影像科
• 2:北京大学第一医院放射科

摘要(Abstract)：

目的 分析胰腺T2信号增高在急性间质水肿性胰腺炎中的诊断价值。方法 收集141例患者的影像与临床资料，资料来自影像归档与存储系统(PACS),且均行磁共振胰胆管成像(MRCP)或上腹部核磁共振(MR)检查，将资料分为对照组及胰腺炎组，进行胰腺/脾(Pb/S)裸眼T_2信号的观察及实测，并分析两者的一致率；比较Pb/ST_2灰度值比(Pb/ST_2ROG)及Pb/S表观扩散系数比值(Pb/SROA)在对照组及胰腺炎组之间的差异；分析Pb/ST_2ROG及Pb/SROA与血淀粉酶浓度之间的相关性，评价Pb/ST_2ROG及胰腺/肝(Pb/L)T_2ROG对急性胰腺炎的诊断效能。结果 以胰腺T_2信号测值为标准，两种观察结果一致率为77.3%;Pb/ST_2ROG在对照组与胰腺炎组之间比较，差异有统计学意义(P<0.05);Pb/SROA在对照组与胰腺炎组之间比较，差异无统计学意义(P>0.05);Pb/ST_2RO与血淀粉酶浓度、Pb/SROA与血淀粉酶浓度均无相关性(P>0.05);经ROC检验显示，Pb/S敏感度、特异度均高于Pb/L。结论 胰腺T_2信号增高对于急性间质水肿性胰腺炎的诊断有一定价值。
Objective To study the diagnostic value of increased pancreatic T_2 signal in acute interstitial edema pancreatitis. Methods The imaging and clinical data of 141 patients were collected from the picture archiving and communication system(PACS) of our hospital, and divided into the control group and the pancreatitis group. Examinations by magnetic resonance cholangiopancreatography(MRCP) or upper abdominal magnetic resonance(MR) were performed among all the patients. The T_2 signal of pancreas/spleen(Pb/S) naked eye was observed and measured. The differences of Pb/ST_2 gray value ratio(Pb/ST_2ROG) and Pb/S apparent diffusion coefficient ratio(Pb/SROA) between the two groups were calculated respectively. The correlation between Pb/ST_2ROG and Pb/SROA and serum amylase concentration was analyzed, while the diagnostic efficacy of Pb/ST_2ROG and Pb/L T_2ROG in acute pancreatitisto was evaluated. Results Using T_(2 )signal measurement of pancreas as the standard, the agreement rate between the two kinds of observation was 77.3%. The difference of Pb/ST_2ROG between the control group and the pancreatitis group was obvious, with statistical significance. There was no statistical significance in Pb/SROA between both groups. There was a positive correlation between Pb/ST_2RO and serum amylase concentration, but the difference was not statistically significant. There was a negative correlation between Pb/SROA and serum amylase concentration, without statistical significance. ROC test showed that the area under the gray value curve of Pb/ST_2 was larger than the pancreas/liver, and with the same cutoff value, the sensitivity and specificity of Pb/S were both higher than Pb/L. signal measurement of pancreas as the standard, and the agreement rate between the two kinds of observation was 77.3%. Pb/ST_2ROG was significantly different between the two groups, with statistical significance. There was no statistical significance in Pb/SROA between the two groups. There was a positive correlation between Pb/ST_2RO and serum amylase concentration, but the difference was not statistically significant. There was a negative correlation between Pb/SROA and serum amylase concentration, and the difference was not statistically significant. ROC test showed that the area under the gray value curve of Pb/ST_2 was larger than the pancreas/liver, and the sensitivity and specificity of Pb/S with the same cut-off value taken, were both higher than Pb/L.Conclusion The increased T_2 signal of the pancreas has certain value in the diagnosis of acute interstitial edema pancreatitis.

关键词(KeyWords)： 胰腺炎;间质水肿性;核磁共振;T_2加权;扩散加权
pancreatitis;interstitial edema;MR;T_2WI;DWI

Abstract:

Keywords:

基金项目(Foundation): 山西省级卫生健康委员会科研课题资助(2020115)

作者(Author): 于萍,唐光健,杨晓霞,许志高,徐建国,杨晓宏
YU Ping,TANG Guangjian,YANG Xiaoxia,XU Zhigao,XU Jianguo,YANG Xiaohong

DOI: 10.19367/j.cnki.2096-8388.2023.08.012

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