贵州医科大学学报

2017, v.42;No.205(10) 1233-1237

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429例不明原因发热患者的病因组成及诊断
Clinical Analysis of 429 Cases of Fever of Unknown Origin

高恺言;邹耀红;袁风红;陈海凤;邹敏超;
GAO Kaiyan;ZOU Yaohong;YUAN Fenghong;CHENG Haifeng;ZOU Mingchao;Department of Rhueumatology & Immunology,the Affiliated Wuxi People's Hospital of Nanjing Medical University;

摘要(Abstract):

目的:分析429例不明原因发热(FUO)患者的病因及确诊方式。方法:收集以FUO收治住院的429例患者临床资料、分析最后诊断、确诊方式及发热病因构成。结果:429例中有321例符合FUO诊断标准,321例中有307例最终明确诊断,确诊率95.64%;感染性疾病引起的发热125例(40.7%),结缔组织病引起的发热130例(42.3%),肿瘤引起的发热29例(9.4%),其它疾病23例(7.5%);108例不符合FUO诊断标准,其中有104例最终明确诊断,确诊率96.3%;感染性疾病引起的发热80例(76.9%),结缔组织病引起的发热15例(14.4%),肿瘤引起的发热5例(4.8%),其它疾病引起的发热4例(3.8%)。结论:结缔组织病和感染性疾病是FUO主要原因,感染性疾病和结缔组织病是非FUO的主要原因。
Objective: To determine the causes for fever of unknown origin( FUO) and improve the accuracy of diagnosis for FUO. Methods: The characteristics,diagnostic methods and etiologies of 429 patients with FUO were retrospectively collected and analyzed in our department during the period from July 2011 to June 2016. Results: 321 out of 429 patients reached the criteria for FUO. 307 patients( 95. 6%) were definitely diagnosed. Connective tissue diseases were the cause for fever in 130 cases( 42. 3%),followed by infections in 125 cases( 40. 7%). Neoplasms in 29( 9. 4%) and other diseases in 23( 7. 5%). 104 cases( 96. 3%) were finally diagnosed out of 108 patients that did not reach the criteria for FUO,in which infections were the cause in 80 cases( 76. 9%),followed by connective tissue diseases in 15 cases( 14. 4%),neoplasms in 5( 4. 8%) and other diseases in 4 cases( 3. 8%). Conclusion: Connective tissue diseases were the leading cause for FUO,followed by infections and neoplasms,while infections were the main cause of fever,followed by connective tissue diseases and neoplasms in non-FUO patients.

关键词(KeyWords): 发热,不明原因;混合性结缔组织病;感染;肿瘤;早期诊断
fever,unknown origin;connective tissue diseases;infections;neoplasms;early diagnosis

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作者(Author): 高恺言;邹耀红;袁风红;陈海凤;邹敏超;
GAO Kaiyan;ZOU Yaohong;YUAN Fenghong;CHENG Haifeng;ZOU Mingchao;Department of Rhueumatology & Immunology,the Affiliated Wuxi People's Hospital of Nanjing Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2017.10.028

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