游经宏,黄品助
YOU Jinghong,HUANG Pinzhu

• 1:监利县人民医院普外科
• 2:中山大学附属第六医院结直肠外科

摘要(Abstract)：

目的:分析经腹腔镜结直肠癌切除术后肠道相关并发症的影响因素。方法:经腹腔镜结直肠癌根治术115例患者分为观察组(发生肠道相关并发症)和对照组(无肠道相关并发症),比较2组患者性别、年龄、体质指数(BMI)、手术时间、术中失血量、糖尿病、冠心病、高血压、呼吸系统疾病、肿瘤部位及术后Dukes分期;对2组有差异指标,采用多因素Logistic回归分析肠道相关并发症发生的影响因素。结果:本组病例中有20例患者发生肠道相关并发症,发生率为17.39%;2组患者的年龄、BMI、糖尿病、呼吸系统疾病及手术时间比较,差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示高龄、合并糖尿病或呼吸系统疾病是经腹腔镜结直肠癌术后发生肠道并发症的危险因素(OR=1.342、1.526、3.514,P<0.05),正常BMI及手术时间短是经腹腔镜结直肠癌切除术后发生肠道并发症的保护因素(OR=0.756、0.851,P<0.05)。结论:高龄、合并糖尿病或呼吸系统疾病是经腹腔镜结直肠癌术后肠道相关并发症的危险因素。
Objective: To evaluate the influencing factors of intestinal related complications after laparoscopic colorectal surgery. Methods: 115 patients after laparoscopic colorectal surgery were divided into observation group( with intestinal related complications) and control group( without intestinal related complications). Observation indexes were compared including their gender,age,body mass index( BMI),operation time,intraoperative blood loss,whether they have diabetes,coronary heart disease,hypertension and respiratory disease,tumor location and postoperative Dukes staging system and multiple logistic regression was used to analyze influencing factors of intestinal related complications if indexes were different. Results: 20 out of 115 patients had intestinal related complications( incidence rate 17. 39%). There were no statistically significant differences in age,BMI,diabetes,respiratory diseases and operation time between two groups( P < 0. 05); multiple logistic regression analysis showed that elderly,concomitant diabetes and respiratory diseases were risk factors for postoperative intestinal complications after laparoscopic colorectal surgery( OR = 1. 342、1. 526、3. 514,P < 0. 05);while normal BMI and shorter operation time were protective factors for postoperative intestinal complications( OR = 0. 756、0. 851,P < 0. 05). Conclusion: Intestinal related complications after laparoscopic colorectal surgery were still affected by age,concomitant diabetes,respiratory diseases,BMI and operation time.

关键词(KeyWords)： 结直肠肿瘤;腹腔镜;手术后并发症;糖尿病;危险因素;回归分析
colorectal cancer;laparoscopy;postoperative complications;diabetes;risk factors;regression analysis

Abstract:

Keywords:

基金项目(Foundation): 广东省自然科学基金(2017A030313580)

作者(Author): 游经宏,黄品助
YOU Jinghong,HUANG Pinzhu

DOI: 10.19367/j.cnki.1000-2707.2018.08.020

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