罗殿熙,许睿,马家玉
Luo Dianxi; et al Laboratory of Affiliated Hospital; Guiyang Medical College ];

• 1:贵阳医学院附院检验科
• 2:广东珠海市中医院
• 3:贵州省公安医院

摘要(Abstract)：

对３２例海洛因依赖者作了血清超氧化物歧化酶（ＳＯＤ）水平测定，其中３０例作了血清ＩｇＧ、ＩｇＡ、ＩｇＭ、Ｃ３、Ｃ４，Ｂｆ以及循环免疫复合物（ＣＩＣ）测定，与年龄匹配的３３例健康志愿者比较，依赖组ＩｇＡ、Ｃ３和ＳＯＤ水平均显著降低（ＩｇＡ、Ｃ３，Ｐ＜０．０１；ＳＯＤ，Ｐ＜０．００１），而ＣＩＣ则显著升高（Ｐ＜０．０１）。提示长期海洛因刺激可损伤机体的Ｉｇ和补体，并影响ＳＯＤ的合成
he IgG,IgA,IgM,C3,C4,Bf and circulatory immune complex (CIC) levels were measured by immunodiffuse or PEG method in sera of 30 heroin addicts, and superoxide dismutase (SOD) levels by radioimmunoassay in 32 those patients. Compared with 33 age matched volunteers, the IgA and C3 levels of the addicts were significantly decreased (1 458±694 mg/L vs 2 091±1 131 mg/L, 725.2±243.9 mg/L vs 992.9±314.4 mg/L, P <0.01, respectively), CIC significantly elevated (2.60±2.35 vs 1.33±0.59, P <0.01) and SOD levels significantly decreased (256.6±54.6 μg/L vs 440.8±205.0 μg/L, P <0.001). These results suggest that the synthesis of immunoglobulin, complement components, and SOD in those people who suffer from chronic heroin stimulating might be impaired.

关键词(KeyWords)： 海洛因瘾,免疫球蛋白,补体,超氧化物歧化酶类
heroin dependence; immunoglobulins; complement; superoxide dismutase

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 罗殿熙,许睿,马家玉
Luo Dianxi; et al Laboratory of Affiliated Hospital; Guiyang Medical College ];

DOI: 10.19367/j.cnki.1000-2707.1996.02.005

参考文献(References)：

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