石微微,杨磊落,莫澜,张雪琳,赖俊,王义平,杜典华,罗钰,吴春维
SHI Weiwei,YANG Leiluo,MO Lan,ZHANG Xuelin,LAI Jun,WANG Yiping,DU Dianhua,LUO Yu,WU Chunwei

• 1:贵州医科大学附属医院体检中心
• 2:贵州医科大学附属医院骨科

摘要(Abstract)：

目的 探究贵阳地区中老年女性骨质疏松症相关因素，为控制疾病的发生提供科学参考。方法 选择贵阳某三甲医院体检中心就诊50岁以上中老年女性658例为研究对象，将是否患有骨质疏松症分为骨质疏松组及非骨质疏松组，比较2组中老年女性的年龄、BMI、绝经年龄、产次、是否定期锻炼、茶饮用频率、牛奶食用频率、患基础疾病种类、是否有家族史、是否吸烟及饮酒等；将两组被检者差异有统计学意义的指标纳入分析变量，采用logistics回归分析影响中老年女性患骨质疏松症的影响因素。结果 658名中老年女性中，患骨质疏松症173例、患病率为26.3%;BMI≥24 kg/m~2、定期锻炼、每周牛奶食用频率≥1次是骨质疏松症的保护因素(P<0.05),OR值分别为0.61、0.54、0.55,95%CI分别为0.43～0.87、0.34～0.86、0.35～0.85;年龄≥65岁、绝经年龄<50岁、产次≥2次、基础疾病≥2种、有家族史、吸烟是其危险因素(P<0.05),OR值分别为4.05、1.87、1.51、2.91、3.95、1.52,95%CI分别为1.75～9.39、1.22～2.85、1.06～2.15、1.70～4.98、1.51～9.83、1.14～2.02。结论 贵阳地区中老年女性骨质疏松症相关因素包括年龄、绝经年龄、锻炼、牛奶饮用频率、产次、基础疾病、家族史及吸烟等，建议采取膳食干预、加强锻炼及戒烟等措施对骨质疏松症进行预防和控制。
Objective To explore the related factors of osteoporosis in middle-aged and old women in Guiyang area, and to provide scientific reference for controlling the occurrence of the disease. Methods Middle-aged and elderly women over 50 years old were selected as the study objects in the physical examination center of a third-grade hospital in Guiyang. Questionnaires were designed to collect relevant information of the study objects. According to the occurrence, middle-aged and elderly women with osteoporosis were selected as the osteoporosis group, and the other middle-aged and elderly women without osteoporosiswere selected as the non-osteoporosis group. The age, BMI, age of menopause, delivery time, whether regular exercise, frequency of tea drinking, frequency of milk consumption, type of underlying diseases, family history, smoking, and drinking were compared between the two groups. The different indicators were included into the analysis variables, and the influencing factors of osteoporosis in middle-aged and elderly women were analyzed by logistics regression. Results A total of 658 individuals were included and the prevalence of osteoporosis was 26.3%. Regular exercise and milk consumption frequency more than once a week were the protective factors for osteoporosis(P<0.05), OR values were 0.61, 0.54 and 0.55,95%CI were 0.43～0.87,0.34～0.86,0.35～0.85; age(>65 years), menopausal age(<50 years), parity(>2 times), basic diseases(>2 kinds), family history, and smoking were the risk factors(P<0.05), OR values were 4.05,1.87, 1.51, 2.91, 3.95 and 1.52, 95%CI were 1.75～9.39,1.22～2.85,1.06～2.15,1.70～4.98,1.51～9.83,1.14～2.02,respectively. Conclusion The related factors of osteoporosis in middle-aged and elderly women in Guiyang include age, menopause age, exercise, frequency of milk drinking, parity, underlying disease, family history, and smoking, etc. It is suggested that measures likedietary intervention, strengthening exercise, quitting smoking and other measures should be provided to prevent and control osteoporosis.

关键词(KeyWords)： 中老年女性;骨质疏松症;危险因素;logistics回归;牛奶;绝经年龄;贵阳
middle-aged and elderly women;osteoporosis;risk factors;logistic regression;milk;menopause age;guiyang

Abstract:

Keywords:

基金项目(Foundation): 贵州省卫生健康委科学技术基金项目(gzwkj2023-040)

作者(Author): 石微微,杨磊落,莫澜,张雪琳,赖俊,王义平,杜典华,罗钰,吴春维
SHI Weiwei,YANG Leiluo,MO Lan,ZHANG Xuelin,LAI Jun,WANG Yiping,DU Dianhua,LUO Yu,WU Chunwei

DOI: 10.19367/j.cnki.2096-8388.2023.09.018

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