贵州医科大学学报

2020, v.45;No.235(04) 456-460

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点阵双极射频联合透明质酸凝胶敷料治疗痤疮凹陷性瘢痕的临床观察
Clinical Observation of Bipolar Fractional Radiofrequency Combined with Hyaluronic Acid Gel in Treating Atrophic Facial Acne Scars

汪凯凡;唐的木;陆洪光;
WANG Kaifan;TANG Dimu;LU Hongguang;Department of Dermatology,Maanshan People's Hospital;Department of Dermatology,the Affiliated Hospital of Guizhou Medical University;

摘要(Abstract):

目的:观察点阵双极射频与透明质酸凝胶敷料联合治疗痤疮凹陷性瘢痕的效果及安全性。方法:66例痤疮凹陷性瘢痕患者均分为试验组、对照1组和对照2组,试验组采用点阵双极射频联合透明质酸凝胶敷料治疗,对照1组仅外用透明质酸凝胶,对照2组仅行点阵射频治疗;计算并比较3组患者的痤疮瘢痕权重评分量表(ECCA)评分以及ECCA改善指数,记录脱痂时间及不良反应。结果:治疗后对照2组、试验组ECCA评分低于对照1组(P <0. 01);对照2组、试验组治疗后ECCA评分比较,差异无统计学意义(P> 0. 05),但试验组ECCA改善指数明显大于对照2组(P <0. 01),平均脱痂时间明显短于对照2组(P <0. 05);对照2组及试验组经点阵双极射频治疗后即刻出现轻微红斑及针尖大小阵列样薄痂1周内完全消退,试验组及对照1组各有2例患者外用透明质酸凝胶敷料过程中出现一过性轻度瘙痒,3组患者治疗结束时均未观察到明显的色素沉着。结论:点阵双极射频治疗痤疮凹陷性瘢痕安全高效,联合外用透明质酸凝胶敷料有助于创面修复。
Objective: To observe the effect and safety of bipolar fractional radiofrequency combined with hyaluronic acid gel in treating atrophic facial acne scars. Methods: Sixty six patients with atrophic facial acne scars were divided into one experimental and two control groups. The experimental group was treated with bipolar fractional radiofrequency combined with hyaluronic acid gel. The control group 1 was only applied with hyaluronic acid gel,while the control group 2 was given bipolar fractional radiofrequency. Atrophic facial acne scar weight scoring was performed using ECCA( echelle d'evaluation clinique des cicatrices d'acne) grading scale,The crust shedding time and side effect in the course of the treatment were observed and recorded. Results: The ECCA scores in the control group 2 and the experimental group after treatment was lower than those in the control group 1( P <0. 01); the difference of the ECCA scores between the control group 2 and the experimental group after treatment was not statistically significant( P > 0. 05),but the improvement index of ECCA score was significantly greater in the experimental group than that in the control group 2( P < 0. 01). In addition,the average scab removal time was significantly shorter in the experimental group than that of the control group 2( P < 0. 05). Moreover,slight erythema with pinpoint size appeared immediately after bipolar radiofrequency treatment in the control group 2 and the experimental group and was completely resolved within one week. One patient in the experimental group and one patient in the control group 1 experienced transient itching during the external application of the hyaluronic acid gel dressing. No obvious pigmentation was observed at the end of treatment in the three groups.Conclusion: Bipolar fractional radiofrequency is safe and effective in treating atrophic facial acne scars,and topical hyaluronic acid gel dressing can help wound repair.

关键词(KeyWords): 痤疮;凹陷性瘢痕;点阵双极射频;透明质酸凝胶;痤疮瘢痕权重评分量表;创面修复
acne;atrophic facial acne scar;bipolar fractional radiofrequency;hyaluronic acid gel;ECCA score;wound repair

Abstract:

Keywords:

基金项目(Foundation): 国家临床重点专科建设项目[卫办医政函(2012)649]

作者(Author): 汪凯凡;唐的木;陆洪光;
WANG Kaifan;TANG Dimu;LU Hongguang;Department of Dermatology,Maanshan People's Hospital;Department of Dermatology,the Affiliated Hospital of Guizhou Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2020.04.015

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