石春花,石明隽,王圆圆,肖瑛,张昌志,孙兰,郭兵

• 1:贵阳医学院病理生理学教研室

摘要(Abstract)：

<正>Wnt基因是一种原癌基因,1982年Nusse等[1]在用小鼠乳头瘤病毒(mouse mammary tumor virus,MMTV)诱导小鼠乳腺癌过程中发现了Wnt基因,由于该基因的激活依赖MMTV的插入(insertion),因此被命名为Int-1。后研究发现Int-1基因与1973年Sharma报道的果蝇的无翅基因Wingless(wg)为同源基因,因此将两者合并称为Wnt基

关键词(KeyWords)： Wnt;β-catenin;信号传导;纤维化

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(编号:81360116);; 贵州省科技厅基金资助项目[No:黔科合J字(2012)2163号]

作者(Author): 石春花,石明隽,王圆圆,肖瑛,张昌志,孙兰,郭兵

DOI: 10.19367/j.cnki.1000-2707.2015.04.001

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