李惠芳
LI Huifang

• 1:无锡市第九人民医院妇产科

摘要(Abstract)：

目的:探讨中药煎服灌肠联合抗生素治疗在慢性盆腔炎急性发作患者中的临床效果。方法:选取56例慢性盆腔炎患者作为研究对象,随机分为观察组和对照组;对照组采用抗生素治疗,观察组采取中药煎服灌肠联合抗生素结合治疗,运用免疫透射比浊法检测C-反应蛋白(CRP)、ELIS法测定白细胞介素-2(IL-2)水平,观察两组治疗总有效率、不良反应发生率以及复发率,比较两组的临床疗效。结果:观察组治疗总有效率(92.86%)高于对照组(71.43%),复发率(7.14%)低于对照组(28.57%),差异有统计学意义(P<0.05),但两组不良反应发生率差异无统计学意义(P>0.05);治疗后与治疗前相比,两组患者IL-2均增加,CRP均降低;观察组与对照组相比,IL-2级CRP变化更加明显,差异有统计学意义(P<0.05)。结论:中药煎服灌肠联合抗生素治疗慢性盆腔炎急性发作临床效果显著,值得推广使用。
Objective: To study the clinical effect of Chinese herbal medicine decoction enema combined with antibiotics in the treatment of acute exacerbation of chronic pelvic inflammatory disease.Methods: Fifty-six patients with chronic pelvic inflammatory disease were randomly divided into observation group and control group,with 28 cases in each. The patients in observation group were given Chinese herbal medicine decoction enema combined with antibiotics,while the patients in the control group received antibiotics only. The levels of IL-2 and CRP,clinical effects,the incidence of adverse reactions and recurrence rates were compared between the two groups. Results: The total effective rate of observation group( 92. 86%) was higher than that in the control group( 71. 43%),P < 0. 05. Recurrence rate of observation group( 7. 14%) was lower than that in the control group( 28. 57%),P <0. 05. There was no significant difference in the incidence of adverse reactions between the two groups( P > 0. 05). After treatment,the level of IL-2 increased in the two groups while the CRP level decreased. Compared with control group,the changes of IL-2 and CRP levels in observation group were more obvious( P < 0. 05). Conclusion: Chinese herbal medicine decoction enema combined with antibiotics in treatment of chronic pelvic inflammatory disease have remarkable clinical effects,and is worthy of promotion.

关键词(KeyWords)： 盆腔炎性疾病;中药疗法;C反应蛋白;白细胞介素2;抗生素;中西医结合;临床效果
chronic pelvic inflammation;traditional Chinese medicine;C reactive protein;interleukin 2;antibiotics;integrated Chinese and western medicine;clinical effect

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 李惠芳
LI Huifang

DOI: 10.19367/j.cnki.1000-2707.2015.10.038

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