贵州医科大学学报

2015, v.40;No.181(10) 1106-1109+1113

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心肌桥近端冠状动脉硬化与颈动脉内膜中层厚度、血脂及心电图的关系
The Relationship between Proximal Coronary Atherosclerosis of Myocardial Bridge and Carotid Intima Media Thickness,Blood lipids and ECG

张兰花,唐翠,邱诗雄,裘佳玉
ZHANG Lanhua,TANG Cui,QIU Shixiong,QIU Jiayu

摘要(Abstract):

目的:探讨心肌桥(MB)患者冠状动脉近端粥样硬化与颈动脉内膜中层厚度(CIMT)、血脂水平及心电图ST-T段的关系。方法:338例拟诊或确诊有冠状动脉疾病并行MDCT冠状动脉成像扫描的患者,共检出MB患者86例及符合条件的47例纳入对照组,按MB近端冠状动脉有无粥样硬化分为MB合并近端粥样硬化组59例与孤立性MB组27例,比较不同组间的CIMT、血脂水平及心电图ST-T段结果。结果:MB患者的CIMT增厚发生率显著高于对照组(P<0.05)。MB合并近端粥样硬化组的CIMT增厚发生率显著高于孤立性MB组,(P<0.05),两组血脂水平及心电图ST-T改变发生率的差异无统计学意义(P>0.05)。≥60岁组的MB近端冠脉粥样硬化发生率显著高于<60岁组(P<0.01)。结论:MB近端冠状动脉硬化与CIMT厚度增加有密切关系,测定MB患者的CIMT厚度对预测评估其近端冠状动脉硬化导致冠心病的风险具有重要意义。
Objective: To explore the relationship between the proximal coronary atherosclerosis of patients with myocardial bridge( MB) and carotid intima media thickness( CIMT),blood lipid and ECG. Methods: A total of 338 patients with suspected or diagnosed coronary artery disease who received MDCT coronary artery imaging were enrolled in this study. 86 cases with MB were detected.According to whether or not there were myocardial bridge proximal coronary artery atherosclerosis,patients were divided into the MB proximal coronary artery atherosclerosis group( MBPCA group,59 cases) and solitary MB group( 27cases). Other qualified 47 cases were included in control group. Then results of CIMT,blood lipids and ECG ST-T were compared and analyzed between groups. Results:The CIMT thickening incidence in MB group was significantly higher than that in control group( P <0. 05) and the incidence of CIMT in MBPCA group was higher than that in solitary MB group( P <0. 05). There was no significant difference in the levels of blood lipids and the ECG ST-T changes between the two groups( P > 0. 05). The incidence of MB proximal coronary atherosclerosis in ≥60years old group was higher than that in < 60 years-old group. Conclusion: There is a close relationship between MB proximal coronary atherosclerosis and the thickening of CIMT. Therefore,the measurement of CIMT thickening in patients with MB is very important for predicting the risk of MB proximal coronary artery atherosclerosis leading to coronary heart disease.

关键词(KeyWords): 冠状动脉粥样硬化;心肌桥;多层螺旋CT;冠状动脉成像;颈动脉内膜中层厚度;血脂水平
coronary atherosclerosis;myocardial bridge;multi slice spiral CT;coronary artery angiography;carotid intima media thickness;blood lipid level

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作者(Author): 张兰花,唐翠,邱诗雄,裘佳玉
ZHANG Lanhua,TANG Cui,QIU Shixiong,QIU Jiayu

DOI: 10.19367/j.cnki.1000-2707.2015.10.031

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