邱昌建,向翠芝,梁尾
QIU Changjian,XIANG Cuizhi,LIANG Wei (Department of Nephrology

• 1:武汉大学人民医院肾内科

摘要(Abstract)：

目的:探讨连续行血液透析滤过(HDF)与血液透析(HD)对尿毒症脑病患者的疗效。方法:尿毒症脑病患者127例随机分为HDF组和HD组,分别采用HDF或HD治疗,于治疗后3个月对患者的肾功能相关指标进行检测。结果:两组患者治疗3个月后BUN、Scr含量均下降,但两组患者的比较无明显差异(P>0.05);治疗后两组患者P3-与PTH均明显降低(P<0.05),两组PTH有明显差异(P<0.05);两组患者治疗后Hb均有不同程度的上升(P<0.05),两组比较有明显差异(P<0.05)。结论:连续行血液透析滤过与血液透析均可有效清除尿毒症小分子毒性物质,但对于大分子毒性物质,HDF治疗方案有效。
Objective: To study the curative effect of continuous hemodiafiltration(HDF) and hemodialysis(HD) on patients with uremic encephalopathy,and to observe related complications.Methods: One hundred and twenty seven patients were randomly divided into groups HDF and HD that received treatment of HDF and HD respectively.Related indexes of renal function were detected in 3 months after treatment.Results: Levels of blood urea nitrogen(BUN),serum creatinine(Scr),parathyroid hormone(PTH) and P3-of the two groups decreased after treatment of 3 months,but the difference between the two groups was not significant(P>0.05).Hemoglobin(Hb) levels increased to some degree after treatment in both the two groups(P<0.05),and the difference between the two groups was significant(P<0.05).Conclusion: Both continuous HDF and HD are effective in clearing small molecular toxic substances,but for clearing of big molecular toxic substances,HDF is more effective.

关键词(KeyWords)： 血液透析滤过;尿毒症;脑疾病
hemodiafiltration;uremia;brain diseases

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 邱昌建,向翠芝,梁尾
QIU Changjian,XIANG Cuizhi,LIANG Wei (Department of Nephrology

DOI: 10.19367/j.cnki.1000-2707.2011.05.018

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