刘琦,周力,袁艺,刘文红
LIU Qi 1; ZHOU Li 1;YUAN Yi 2; LIU Wen hong 2 (1.Department of Digestive Internal Medicine;

• 1:贵阳医学院附院消化内科
• 2:贵阳医学院附院消化内科
• 3:贵阳医学院附院供应室
• 4:贵阳医学院附院供应室 贵州贵阳550004

摘要(Abstract)：

目的 :研究急性胰腺炎时的血脂水平及探讨两者之间所存在的关系。方法 :使用全自动生化分析仪动态测定轻型急性胰腺炎 (MAP)患者 35例 ,重症急性胰腺炎 (SAP)患者Ⅰ级 15例 ,Ⅱ级 17例的血清总胆固醇(TC)和甘油三酯 (TG)水平。结果 :在急性胰腺炎急性反应期 ,均有血脂升高 ,随着病情明显好转 ,高脂血症逐渐恢复正常。MAP患者于发病后第 1周TC为 (4 11± 2 78)mmol/L ,TG为 (2 2 9± 1 5 1)mmol/L ;SAPⅠ级患者于发病后第 4周TC为 (4 2 4± 2 79)mmol/L ,TG为 (2 13± 1 32 )mmol/L。而预后较差的患者高脂血症未得到恢复 ,SAPⅡ级患者于发病后第 4周TC为 (10 96± 5 88)mmol/L ,TG为 (7 91± 3 95 )mmol/L。结论 :急性胰腺炎易并发高脂血症 ,而持续的高脂血症能加重胰腺炎症 ,可能是致命预后的一项参数
Objective: To study the relationship between acute pancreatitis and serum lipid contents. Methods: Serum levels of total cholesterol and triglyceride in 35 patients with mild acute pancreatitis(MAP) and 32 with severe acute pancreatitis (SAP) were continuously determined with automatic biochemical analytical apparatus. Results: Hyperlipidemia was observed in acute period, and the lipid contents dropped to normal level along with convalesce of patients. However, the hyperlipidemia in critical patients with unfavourable prognosis did not get renewal. Conclusion: Hyperlipidemia is common complication in patients with acute pancreatitis. Persistent hyperlipidemia may aggravate the crisis, and this appeared to be an index of fatal prognosis.

关键词(KeyWords)： 胰腺炎;急性病;高脂血症
pancreatitis; acute disease; hyperlipidemia

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 刘琦,周力,袁艺,刘文红
LIU Qi 1; ZHOU Li 1;YUAN Yi 2; LIU Wen hong 2 (1.Department of Digestive Internal Medicine;

DOI: 10.19367/j.cnki.1000-2707.2003.03.014

参考文献(References)：

• [1]中华医学会外科学会胰腺学组.急性胰腺炎的临床诊断及分级标准(1996年第二次方案)[J].中华外科杂志,1997,35(12):773-775.
• [2]VanGossumA ,LemoyneM ,GreigPD ,etal.Lipid associatedtotalparenteralnutritioninpatientswithsevereacutepancre atitis[J].JpenJParenterNutr,1988,12(3):250-255.
• [3]BassVD ,HoffmannWE ,DornerJL .Normalcaninelipidprofilesandeffectsofexperimentallyinducedpancreatitisandhepaticnecrosisonlipids[J].AmJVetRes,1976,37(11):1355-1357.
• [4]ChikamuneT ,KatamotoH ,NomuraK ,etal.Lipoproteinprofileincaninepancreatitisinducedwitholeicacid[J].JVetMedSci,1998,60(4):413-421.
• [5]林庚金.急性胰腺炎[M].见:陈灏珠.实用内科学.第10版[M ].北京:人民卫生出版社,1998.1649-1657.

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