贵州医科大学学报

2006, (04) 336-338

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紫苏子对高脂血症大鼠血脂水平的影响
Experimental Study of the Effect of Perilla frutescens Seed on Hyperlipoidemia Model Rats

王雨;刘佳;高敏;俞红;吴克枫;阮海星;朱彩霖;
WANG Yu,LIU Jia,GAO Min,YU Hong,WU Ke-feng,RUAN Hai-xing,ZHU Cai-lin(Guizhou Provincial Center for Disease Control and Prevention,Guiyang 550004,China)

摘要(Abstract):

目的:研究紫苏子对高脂血症模型大鼠的降血脂作用。方法:用0.8、4.2、25.0 g/kg剂量的紫苏子连续喂饲大鼠30 d,取血清测定大鼠血清胆固醇(TC)、甘油三脂(TG)及高密度脂蛋白胆固醇(HDL-C)含量。结果:紫苏子能明显降低TC和TG含量,但对HDL-C的水平无显著影响。结论:紫苏子可降低高脂血症大鼠血脂水平。
Objective: To study the blood lipid reducing effect of Perilla frutescens seed in hyperlipoidemia model rats.Methods: Rats in treatment groups were continually given P.frutescens seed at doses of 0.8,4.2,25.0g/kgBW separately for 30 days.The serum levels of TC,TG and HDL-C of rats were examined on the 30~(th) day.Results: The serum contents of TC and TG in treated rats were markedly less than those of non-treated model group,while the level of HDL-C was not reduced.Conclusions: P.frutescens seed could reduce the level of blood lipids,except HDL-C,in rats.

关键词(KeyWords): 紫苏子;胆固醇;甘油三脂类;脂蛋白类,HDL;大鼠
Perilla frutescens seed;cholesterol;triglycerides;lipoproteins,HDL;rats

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作者(Author): 王雨;刘佳;高敏;俞红;吴克枫;阮海星;朱彩霖;
WANG Yu,LIU Jia,GAO Min,YU Hong,WU Ke-feng,RUAN Hai-xing,ZHU Cai-lin(Guizhou Provincial Center for Disease Control and Prevention,Guiyang 550004,China)

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DOI: 10.19367/j.cnki.1000-2707.2006.04.014

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