王世平,吴艳俊,李玲,张金娟,吴君
WANG Shiping,WU Yanjun,LI Ling,ZHANG Jinjuan,WU Jun(Department of Functional Laboratory

• 1:贵阳医学院机能学实验室

摘要(Abstract)：

目的:对青牛胆的化学成分进行研究。方法:应用硅胶、Sephadex LH-20、RP-18柱色谱进行分离、纯化,根据理化常数和光谱分析鉴定结构。结果:从青牛胆中分离出5个化合物,经鉴定为:20β-羟基蜕皮素(Ⅰ)、金果榄苷(Ⅱ)、非洲防己碱(Ⅲ)、尖防己碱(Ⅳ)、药根碱(Ⅴ)。结论:化合物Ⅴ为首次从该植物中分离得到。
Objective:To study the chemical constituents of Tinospora sagittata.Methods: Various chromatographic techniques including silica gel,Sephadex LH-20,and RP-18 trabeculum were used to isolate the constituents of T.sagittata,and their structures were identified by spectral and chemical methods.Result: Five compounds were isolated from T.sagittata,and their structures were identified as 20β-hydroxy-ecdysone(Ⅰ),tinoside(Ⅱ),columbamine(Ⅲ),acutumine(Ⅳ),and jatrorrhizine(Ⅴ).Conclusion: This is the first report that compound Ⅴbeing isolated from T.sagittata.

关键词(KeyWords)： 色谱法,薄层;青牛胆;化学成分
chromatogrphy,thin layer;T.sagittata;chemical constituents

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(No.30471592)

作者(Author): 王世平,吴艳俊,李玲,张金娟,吴君
WANG Shiping,WU Yanjun,LI Ling,ZHANG Jinjuan,WU Jun(Department of Functional Laboratory

DOI: 10.19367/j.cnki.1000-2707.2011.01.004

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