贵州医科大学学报

1987, (02) 156-158

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心得安与酚妥拉明治疗流行性出血热的临床观察
CLINICAL OBSERVATION OF THE TREATMENT WITH PROPRANOLOL AND PHENTOLAMINE IN EPIDEMIC HEMORRAGIC FEVER

周思礼;
Zhou Sili Suiyang county people's hospital

摘要(Abstract):

心得安与酚妥拉明治疗流行性出血热(EHF)40例(治疗组),与对症治疗40例(对照组)比较。结果:治疗组的少尿肾衰发生率为18.8%,病死率为2.5%,均低于对照组(分别为41.4%,7.5%)P<0.05);治疗组的越期率为75%,明显高于对照组的55.2%(P<0.05)。表明心得安与酚妥拉明可能具有增加肾脏的血流量,加速毒物排出的作用。
Fourty cases of epidemic hemorrhagic fever(EHF)treated with propranolol and phentolamine were compared with another 40 patients,using conservative symptomatic therapy as control group.20 mg propranolol orally three times per day and 20~80mg phentolamine intravenously per day were given to the therapeutic group.Until the polyuria stage and relief of symptoms of uremia have been attained.The result of the treatment was as follows:the mortality in therapeutic group was lower than that of the control group(P<0.05),while the over stage rate was markedly higher than that of the control group(P< 0.05).The result showed that propranolol and phentolamine may have the eff- ects of alleviating the renal damage,increasing the renal blood flow and acce- lerating the excretion of toxic material.

关键词(KeyWords): 心得安;酚妥拉明;流行性出血热
Propranolol;Phentolamine;Hemorrhagic fever;epidemic

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作者(Author): 周思礼;
Zhou Sili Suiyang county people's hospital

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DOI: 10.19367/j.cnki.1000-2707.1987.02.015

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