贵州医科大学学报

1986, (02) 142-145

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猪胸腺素组分Ⅴ治疗乙型病毒性肝炎疗效观察
THE CLINICAL TRIAL OF PIG THYMOSIN FRACTION V IN TREATING VIRAL HEPATITIS B

錢定毅;袁贵容;潘永芳;李政;梁斯璧;周庆均;梁熾南;叶秉三;
Qian Dingyi, et al Dep. of Infectious disease

摘要(Abstract):

胸腺素为免疫调节药物,其治疗病毒性肝炎疗效尚未确定,需进行研究。作者等采用随机分配、复合处理对照及盲法,观察用猪胸腺素组分V治疗HBsAg阳性乙型迁延性病毒性肝炎19例的疗效。用药剂量:20mg.I.M.,q.d.,20天为一疗程,间隔7~8天再用一疗程。治后未见有明显促使HBsAg阴转或近期临床恢复的效果。另外,作为预试,用该药治疗HBsAg阳性乙型慢性病毒性肝炎5例,疗程同上,治后无一例HBsAg阴转。
The prelirainary observation on clinical trial of pig thymosin fraction V In treating viral hepatitis B are reported. 28 HBsAg positive cases of chronic persistent viral hepatitis were randomly divided into experimental and control groups. There were 19 cases in experimental group treated by pig thymosin fraction V (20 mg intramuscularly q. d. for 20 days, and repeated in the same doses with a week interval) and 9 cases treated with placebo. There was no statistical significant difference between the groups after 2 courses of treatraent, in either clinical improvement or negative conversis rate of HBsAg. Beside the 5 HBsAg positive cases of chronic active viral hepatitis B treated by pig thymosin fraction V as above still remained HBsAg positive and without clinical improvement. In short, there was no satisfactory effect of pig thyraosin fraction Y in treating viral hepatitis B.

关键词(KeyWords): 胸腺索组分V;乙型病毒性肝炎
Thymosin fraction V Viral hepatitis B

Abstract:

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作者(Author): 錢定毅;袁贵容;潘永芳;李政;梁斯璧;周庆均;梁熾南;叶秉三;
Qian Dingyi, et al Dep. of Infectious disease

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DOI: 10.19367/j.cnki.1000-2707.1986.02.016

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