徐洁,关忠伟
XU Jie1,GUAN Zhongwei2(1.Department of Biotherapy

• 1:中国医科大学第四附属医院生物治疗科
• 2:中国医科大学第四附属医院结核科

摘要(Abstract)：

目的:观察宣泄和认知干预对胃癌患者化疗期间生活质量影响。方法:55例胃癌患者化疗期间接受情绪宣泄和癌症知识认知治疗,1次/5～7 d,共6周;在化疗1周时及化疗结束3 d内使用欧洲癌症研究与治疗组织(EORTC)针对胃癌特点设计的胃癌患者生活质量调查问卷(OLQ-STO22)评估,并与54例未进行宣泄和认知干预的同病化疗患者(对照组)比较。结果:两组患者化疗1周时QLQ-STO22问卷比较,各分量表评分接近;化疗结束后,干预组的吞咽困难、胃部疼痛、呃逆、饮食受限、焦虑、口干、味觉、身体外观等分量表评分明显优于化疗1周时(P<0.05或P<0.01),也优于同期对照组结果(P<0.05)。结论:宣泄和认知干预可明显改善胃癌患者化疗期间生活质量。
Objective:To evaluate the effect of abreaction and cognition on life quality improving for gastric cancer patients during chemical therapy.Methods: A total of 55 patients with gastric cancer(experimental group,group E) were given abreaction and cognition treatment,once every 5～7 days,for 6 successive weeks.A survey according to OLQ-STO22 published by European Organization for Research on Treatment of Cancer(EORTC) was carried out to them and other 54 gastric cancer patients not received abreaction or cognition treatment(control group,group C),and the results were compared.Results: scores of the two groups were similar in the first week.After chemical therapy,scores of dysphagia,gastric pain,hiccup,drink and food limitation,anxiety,dry mouth,gustatory sensation,and body appearance in group E were superior to group C in the first week(P<0.05) and in the end of chems.Conclusions: Abreaction and cognition intervention could remarkably improve life quality of gastric cancer patients during chemical therapy.

关键词(KeyWords)： 癌;胃;宣泄和认知干预;生活质量;抗肿瘤联合化疗方案
carcinoma;stomach;antineoplastic combined chemotherapy protocls;abreaction and cognition;quality of life

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 徐洁,关忠伟
XU Jie1,GUAN Zhongwei2(1.Department of Biotherapy

DOI: 10.19367/j.cnki.1000-2707.2010.02.014

参考文献(References)：

• [1]姜宝法,徐涛,刘春晓,等.胃癌患者生活质量问卷(QLQ-STO22)中文版的制定[J].中国心理卫生杂志,2005(5):310-312.
• [2]Linden W,Yi D,Barroetavena MC,et al.Developmentand validation of a psychosocial screening instrument forcancer[J].Health Qual Life Outcomes,2005(3):54.
• [3]Ingram SS,Seo PH,Sloane R,et al.The association be-tween oral health and general health and quality of life inolder male cancer patients[J].J Am Geriatr Soc,2005(9):1504-1509.
• [4]金玉彬刘红泽刘闫.心理干预治疗对胃癌患者化疗后心理状态影响的临床观察[J].实用肿瘤学杂志,2007(4):397-399.
• [5]娄书花,郝玉凤,马冬萍.心理治疗对癌症化疗患者焦虑及胃肠反应影响的临床研究[J].中国康复医学杂志,2005(8):604-605.
• [6]梅逸静,王欢,李福莲,等.认知干预对胃肠道恶性肿瘤患者术后恶心呕吐的影响[J].中华肿瘤防治杂志,2005(17):1359-1361.

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