贵州医科大学学报

1987, (02) 108-111+205

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对嗜碱性粒细胞脱颗粒试验(间接法)诊断过敏性休克的评价
EVALUATION OF BASOPHIL DEGRANULATION TEST(INDIRECTMETHOD)FOR DIAGNOSIS OF ANAPHYLACTIC SHOCK

王恩寿;张克维;王磊;王杰;屈剑平;
Wang Enshou Dep of Forensic Medicine

摘要(Abstract):

本文借助豚鼠过敏性休克模型的复制,重复了某些文献利用嗜碱性粒细胞脱颗粒试验(间接法)(甲苯胺蓝染色;中性红染色)对过敏性休克的诊断。结果证实:(一)我们的实验支持 Preedman(1982)等的观点,认为脱颗粒试验(间接法)目前尚处于实验室阶段,不能过早用于临床;(二)中性红染色,家兔各类型白细胞胞浆中均出现石榴红色颗粒。因而此法应予摒弃。
Basophil degranulation test(indirect method)(toluidine blue stain and neutral red stain),by using the model of experimental anaphylactic shock of guinea- pig,was repeated similarly,according to the literature published in recent time.The results of our study confirmed following facts:(1)the point of veiw of Freedman(1982)that the degranulation test(indirect method)was still being in the laboratorial stage,and could not be used in the clinical pract- ice,as a method to find out the certain antigen or at a diagnostic method of anaphylactic disease,was supported by our experimental works.(2)by neutr- al red stain,there were alarge amount of red granules in the cytoplasm of all kin- ds of the white blood cells,therefore,this stainning method would be ruled out from the stainning methods used for study the basophil degranulation test.

关键词(KeyWords): 过敏性休克;嗜碱性粒细胞脱颗粒试验
Anaphylactic shock The basophil degranulation test

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作者(Author): 王恩寿;张克维;王磊;王杰;屈剑平;
Wang Enshou Dep of Forensic Medicine

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DOI: 10.19367/j.cnki.1000-2707.1987.02.003

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