伍国锋，陈婉梅，闫剑群
Wu Guofeng;

• 1:贵阳医学院神经病学教研室，西安医科大学神经生理学研究室

摘要(Abstract)：

采用微电极细胞外记录技术，以清醒大鼠脊髓背角广动力范围（ＷＤＲ）神经元的晚串放电频率为指标，观察损毁延髓外侧网状核（ＬＲＮ）前后高频高强度电针对ＷＤＲ神经元的作用。结果表明：高频高强度电针可明显抑制ＷＤＲ神经元对外周伤害性刺激的反应，电针的这种抑制作用似乎并不受ＬＲＮ的调控。
WDR neurones in the spinal dorsal horn have been demonstrated to play an important role in nociceptive transmission. The present study was designed to examine the effect of electroaccupuncture on WDR neurones by the method of recording unit discharges of WDR neurones in the rat spinal dorsal horn before and after damaging the rat's LRN.Electroaccupuncture (EA) with high-freqency and highintensity significantly decreased the noxious-evoked discharges of WDR neurones be fore the damage of LRN. EA with the same parameters also significantly inhibited the discharges induced by noxious-stimulation after the LRN was destroyed. No significant differences in EA inhibition rate before and after the damage of LRN were observed, indicating that the inhibition of EA on WDR neurones was not controlled by LRN.

关键词(KeyWords)： 电刺激，延髓，网状核
electric stimulation;medulia oblongata;lateral reticular nucleus

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 伍国锋，陈婉梅，闫剑群
Wu Guofeng;

DOI: 10.19367/j.cnki.1000-2707.1995.03.005

参考文献(References)：

• lWoolfCJ，etal．Antinociceptiveeffectofperipheralsegmentalelectricalstimulationintherat．Pain，1988，8：237－2522PomeranzB，etal．Suppresionofnoxiousresponsesinsingleneuronesofcatspinalcordbyelectro－accupunctureanditsreversalbytheopiateantaganistsnaloxone．ExpNeurol，1979，64：327－3413PomeranzB，etal．Accupuncturereduceselectrophysiologicalandbehavioralresponsestonoxiousstimuli：pituitaryisimplicated．ExpNeurol，1977，54：172－1784韩济生。针刺镇痛及其有关的神经通路和神经递质。生理科学进展，1984，15：294～3005杜焕基。损毁和刺激蓝斑复合核对内脏躯体反射抑制效应的影响。生理学报，1979，31：153～1626唐敬师。各类传入纤维在不同条件下的电针镇痛作用及其机制的探讨。西安医科大学报，1983，4：1～67谢亦宽，延髓下部单胺类神经元及其神经介质对脊髓痛敏神经元的影响。中国科学，1981，3：377～384

文章评论(Comment)：