张汉群,倪婷婷,鲁亮,薛英波,谭诗生,杨飞月,李杭

• 1:贵州省人民医院肿瘤科
• 2:遵义医学院

摘要(Abstract)：

目的:探讨放化疗同步治疗晚期鼻咽癌的近期临床有效率、毒副反应及病人的耐受性。方法:63例Ⅲ～Ⅳ期鼻咽癌初治患者采用随机法分为实验组和对照组,实验组采用TP方案:紫杉醇和顺铂;对照组采用PF方案:顺铂和氟尿嘧啶;两组放疗方法相同,同时给予相同剂量照射。结果:两组近期有效率:TP组为97%,PF组为93%,两组比较差异无统计学意义(P(0.05);白细胞减少、恶心呕吐及口腔黏膜炎的发生率PF组高于TP组,差异有统计学意义(P(0.05);其余毒副反应评价差异无统计学意义(P(0.05)。结论:TP方案联合放疗治疗晚期鼻咽癌近期有效率肯定,毒副反应较轻,病人耐受性好。

关键词(KeyWords)： 鼻咽肿瘤;顺铂;氟尿嘧啶;紫杉醇;放化疗同步

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 张汉群,倪婷婷,鲁亮,薛英波,谭诗生,杨飞月,李杭

DOI: 10.19367/j.cnki.1000-2707.2011.01.028

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