贵州医科大学学报

2017, v.42;No.197(02) 202-204+208

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

不同程度宫颈病变患者血清中鳞状上皮细胞癌抗原水平
Changes of Squamous Cell Carcinoma Antigen in Cervical Lesions

赵轩胤;吴晓玲;
ZHAO Xuanyin;WU Xiaoling;Department of Gynecology,the Affiliated Hospital of Guizhou Medical University;

摘要(Abstract):

目的:观察血清鳞状上皮细胞癌抗原(SCC-Ag)在宫颈病变及宫颈鳞癌手术前后的变化。方法:30例宫颈上皮内瘤变患者(CIN组)、107例宫颈鳞癌患者(宫颈癌组)及30例同期体检健康妇女(正常对照组),采用化学发光微粒子免疫分化法(CMIA)测定正常对照组体检时、宫颈癌患者入院和手术后不同时间(1、2及3月)血清SCC-Ag浓度,比较正常对照组、CIN组及宫颈癌组入院时血清SCC-Ag水平及阳性率,入院时不同临床分期宫颈癌患者SCC-Ag水平及阳性率,宫颈癌患者入院时及手术后不同时间点(术后1、2、3月)SCC-Ag水平及阳性率。结果:3组被检者血清SCC-Ag水平及阳性率比较,正常对照组Objective:To observe changes of serum squamous cell carcinoma(SCC) antigen(SCCAg) in cervical lesions and in patients before and after operation of cervical SCC.Methods:Subjects included 30 cervical intraepithelial neoplasia patients(group CIN),107 SCC patients(group SCC),and 30 healthy women(normal control group).Serum SCC-Ag concentrations of control group and those of group SCC in different time points(at admission,and in 1,2 and 3 months after operation)were determined by chemiluminescence micro particles(CMIA).The levels and positive rates of SCCAg among control group,group CIN,and that of group SCC at admission were compared,as well,the SCC-Ag levels and positive rates of group SCC with different clinic stages,and at different time points(at admission,and in 1,2 and 3 months after operation) were compared.Results:The serum levels of SCC-Ag in group SCC was significantly higher than those of group CIN and normal control group.But only the difference between groups CIN and SCC was significant(P < 0.05),although if compare the 3 groups together,the difference was statistically significant(P < 0.05).The level and SCC-Ag positive rate of SCC patients increased with the clinic stages,and the differences were statistically significant(P < 0.05).The level and SCC-Ag positive rate of patients in group SCC was lower after operation than before,and had a tendency that decreased along with the post-operation time increased.Thedifferences was significant(P < 0.05).Conclusion:Serum SCC-Ag has some clinic value in diagnosis,treatment,and postoperative recurrence monitoring of cervical SCC.

关键词(KeyWords): 鳞状上皮细胞癌抗原;宫颈病变;宫颈癌;术后监测
squamous cell carcinoma antigen;cervical lesions;cervical cancer;postoperative monitoring

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 赵轩胤;吴晓玲;
ZHAO Xuanyin;WU Xiaoling;Department of Gynecology,the Affiliated Hospital of Guizhou Medical University;

Email:

DOI: 10.19367/j.cnki.1000-2707.2017.02.018

参考文献(References):

文章评论(Comment):

序号(No.) 时间(Time) 反馈人(User) 邮箱(Email) 标题(Title) 内容(Content)
反馈人(User) 邮箱地址(Email)
反馈标题(Title)
反馈内容(Content)
扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享