文蜀怡,赵立新,宋俊林
WEN Shu-yi; ZHAO Li-xin; SONG Jun-lin (The Affiliated Hospital of Guizhou Aluminum Factory;

• 1:贵州铝厂职工医院
• 2:贵州铝厂职工医院
• 3:贵州铝厂职工医院 贵州贵阳550014
• 4:贵州贵阳550014

摘要(Abstract)：

目的 :观察肝炎、肝硬化患者血钙浓度变化。方法 :用OCPC比色法对 2 4 4例急、慢性肝炎及肝硬化患者做血钙浓度测定 ,同时设正常对照组 74例。结果 :对照组血钙浓度均值 (2 30± 0 2 6 )mmol/L ,无血钙 <2 0 3mmol/L者 ;急性肝炎组血钙浓度均值 (2 2 5± 0 2 5 )mmol/L ,血钙 <2 0 3mmol/L者 5例 ,占 6 2 % (5 / 81) ;慢性肝炎组血钙浓度均值 (2 2 1± 0 2 3)mmol/L ,血钙 <2 0 3mmol/L者 2 7例 ,占 35 5 % (2 7/ 76 ) ;肝硬化组血钙浓度均值(1 90± 0 2 7)mmol/L ,血钙 <2 0 3mmol/L者 6 6例 ,占 75 9% (6 6 / 87) ,肝硬化组与前三组分别相比 ,有显著性差异(P <0 0 1)。肝硬化A级血钙均值 (2 15± 0 2 3)mmol/L ,血钙 <2 0 3mmol/L者 8例 ,占 9 2 % (8/ 87) ;B级血钙均值 (1 91± 0 2 1)mmol/L ,血钙 <2 0 3mmol/L者 2 3例 ,占 2 6 4 % (2 3/ 87) ;C级血钙均值 (1 84± 0 2 0 )mmol/L ,血钙<2 0 3mmol/L者 35例 ,占 4 0 2 % (35 / 87) ,C组与A ,B二组分别比较 ,有显著性差异 (P <0 0 1)。结论 :血钙浓度可作为判断肝炎与肝硬化病情严重程度及预后的重要指标
Objective: To observe the changes of blood calcium density (BCD) of hepatitis patients and liver cirrhosis patients. Method: BCD of 244 cases of acute and chronic virus hepatitis (AH and CH) and liver cirrhosis (LC) from Jan. 2000 to Jun. 2003 and 74 normal people (CG) were checked and analyzed. Results: The average BCD of CG was (2.30±0.26) mmol/L,and none of them was below 2.03 mmol/L; The average BCD of AH and CH were (2.25±0.25) mmol/L and (2.21±0.23) mmol/L and the rates of BCD below 2.03 mmol/L were 6.2% (5/81) and 35.5%(27/76)respectively; The average BCD of LC was (1.90±0.27) mmol/L. Among them, BCD of 66 people were below 2.03 mmol/L, and the rate was 75.9%(66/87); There were significant differences among the four groups (P<0.01). The average BCD of grade A, grade B and grade C of LC patients were (2.15±0.23) mmol/L,(1.91±0.21) mmol/L,and (1.84±0.20) mmol/L, and the rates of BCD below 2.03 mmol/L were 9.2%(8/87), 26.44%(23/87)and 40.2%(35/87)respectively; There were significant differences among grade A,B and C of LC patients (P<0.01). Conclusion: BCD could be used as an important index to reflect the disease status of hepatitis and liver cirrhosis patients and is helpful with prognosis.

关键词(KeyWords)： 肝炎,病毒性,人;肝硬化;血钙
hepatitis,viral human; liver cirrhosis; blood calcium

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 文蜀怡,赵立新,宋俊林
WEN Shu-yi; ZHAO Li-xin; SONG Jun-lin (The Affiliated Hospital of Guizhou Aluminum Factory;

DOI: 10.19367/j.cnki.1000-2707.2004.03.014

参考文献(References)：

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• [2]何云,袁凤仪,程明亮,等.肝病与全身系统疾病诊断治疗学[M].北京:人民军医出版社,2002.336.
• [3]张玉,徐三荣,蒋蔚如.肝硬化患者血钙浓度的临床评价[J].中华消化杂志,2002,22:768

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