共培养条件下血管内皮细胞调控平滑肌细胞功能的研究进展
褚孟洋,张丽君,徐沁,李程飞,石菲,高原,孙喜庆,赵疆东,王永春
摘要(Abstract):
<正>血管内皮细胞和平滑肌细胞是构成血管壁的主要细胞,两者在结构上相邻,在功能上交互调控,在血管功能及结构改变中扮演着重要角色。平滑肌细胞是内皮细胞的周细胞之一,具有舒缩和重建血管的作用,内皮细胞不仅是血管的内衬,还可分泌多种因子调节平滑肌细胞的形态、表型、增殖、迁移和舒缩等功能,是平滑肌细胞的生长调节器。两种细胞的相互调节在维持血管的正常功能中发挥
关键词(KeyWords):
血管内皮细胞;平滑肌细胞;形态;表型;增殖;迁移;共培养
基金项目(Foundation): 国家自然科学基金项目(81372130,81301681,81471817)
作者(Author):
褚孟洋,张丽君,徐沁,李程飞,石菲,高原,孙喜庆,赵疆东,王永春
DOI: 10.19367/j.cnki.1000-2707.2017.06.001
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