毛志强,蒋迪,吴国谦,黎润球,叶贝华,何锦添
MAO Zhiqiang,JIANG Di,WU Guoqian,LI Runqiu,YE Beihua,HE Jintian

• 1:东莞市人民医院

摘要(Abstract)：

目的:探讨低温等离子射频消融术(RFA)辅助鼻内镜对慢性鼻—鼻窦炎(CRS)的治疗效果。方法:110例CRS患者均分为联合组和对照组,联合组患者采用RFA辅助鼻内镜手术治疗、对照组采用标准内镜手术治疗;比较2组患者治疗前及治疗后头痛、面部疼痛、鼻塞、嗅觉障碍及喷嚏的视觉模拟量表(VAS)评分,比较鼻黏膜纤毛清除率、鼻黏膜纤毛清除速度及鼻腔鼻窦结局测试(SNOT-20)评分,比较2组患者鼻黏膜水肿、黏膜出血及黏膜干燥等手术并发症发生率。结果:治疗前,2组患者头痛、面部疼痛、鼻塞、嗅觉障碍及喷嚏VAS评分,鼻黏膜纤毛清除率、鼻黏膜纤毛清除速度及SNOT-20评分比较,差异无统计学意义(P>0.05);治疗后,2组患者头痛、面部疼痛、鼻塞、嗅觉障碍、喷嚏VAS评分及SNOT-20评分显著低于治疗前,联合组显著低于对照组,2组患者鼻黏膜纤毛清除率、鼻黏膜纤毛清除速度显著高于治疗前,联合组显著高于对照组,差异有统计学意义(P<0.05);2组患者并发症率比较,差异无统计学意义(P>0.05)。结论:RFA辅助鼻内镜手术对CRS患者的治疗优于标准内镜手术,能更好地改善患者鼻黏膜纤毛功能。
Objective: To investigate the treatment of chronic rhinosinusitis with low temperature plasma radiofrequency ablation assisted endoscopy. Methods: 110 CRS patients were divided into combined group and control group, and the patients in the combined group were treated with RFA assisted endoscopic surgery and the control group with standard endoscopic surgery. The scores of visual analogue scale(VAS) for headache, facial pain, nasal congestion, olfactory impairment and sneezing were compared before and after treatment. The nasal mucosal cilia clearance rate, nasal mucosal cilia clearance rate and nasal sinus outcome test(SNOT-20) score were compared, and the incidence of surgical complications such as nasal mucosal edema, mucosal bleeding and mucosal dryness were compared in two groups. Results: Before treatment, headache, facial pain, nasal congestion, olfactory impairment and sneezing VAS score, nasal mucosal cilia clearance rate, nasal mucosal cilia clearance rate and SNOT-20 score were compared between the two groups, and the difference was not statistically significant(P>0.05). After treatment, headache, facial pain, nasal congestion, olfactory impairment, sneezing VAS score and SNOT-20 score were significantly lower in group 2 than before treatment, and the combined group was significantly lower than the control group. The clearance rate of nasal mucosa cilia was higher than that before treatment. The combined group was significantly higher than the control group, and the difference was not statistically significant(P<0.05). There was no significant difference in the complication rate among the two groups(P>0.05). Conclusion: The treatment of CRS patients with RFA assisted endoscopy is better than that of standard endoscopic surgery, which can improve the function of nasal mucosal cilia.

关键词(KeyWords)： 射频消融术,低温;鼻内镜手术;慢性鼻-鼻窦炎;视觉模拟量表评分;鼻腔鼻窦结局测试评分;并发症
radiofrequency ablation,hypothermia;endoscopic surgery;chronic rhinosinusitis;visual analogue scale score;nasal sinus outcome test score;complications

Abstract:

Keywords:

基金项目(Foundation): 东莞市科学技术局课题资助(2018507150011326)

作者(Author): 毛志强,蒋迪,吴国谦,黎润球,叶贝华,何锦添
MAO Zhiqiang,JIANG Di,WU Guoqian,LI Runqiu,YE Beihua,HE Jintian

DOI: 10.19367/j.cnki.1000-2707.2020.01.022

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