浓替硝唑含漱液治疗智齿冠周炎的临床疗效Clinical Efficacy of Concentrated Tinidazole Gargles on Pericoronitis of Wisdom Tooth
侯豫
HOU Yu
摘要(Abstract):
目的:观察浓替硝唑含漱液局部应用治疗冠周炎的临床疗效。方法:将80例冠周炎患者随机分成观察组和对照组,每组40例,观察组采用浓替硝唑含漱液局部治疗,对照组采用传统的双氧水、生理盐水局部治疗;观察治疗后第3天两组冠周炎患者的临床疗效及对4类口腔厌氧菌的杀菌效果及清除率。结果:治疗后,观察组和对照组患者的总有效率分别为100%和65%,观察组的有效率明显高于对照组,差异有统计学意义(P<0.05);两组患者治疗后,对4类口腔主要厌氧菌均有一定的杀菌效果,总清除率分别为72%和49%,差异有统计学意义(P<0.05)。结论:浓替硝唑含漱液局部治疗冠周炎疗效显著,值得临床推广应用。
Objective: To observe the clinical efficacy of concentrated tinidazole gargles on pericoronitis. Methods: Eighty cases with pericoronitis were randomly divided into experimental group treated with concentrated tinidazole gargles and control group treated with conventional hydrogen peroxide and saline. Clinical efficacy of both the two groups in the 3rdday after treatment was observed,bactericidal effect and clearance rate of the four kinds of oral anaerobes were detected. Results: The clinical efficacy of the experimental group and the control group was 100% and 65% respectively,and the difference was significant( P < 0. 05). Bactericidal effect on the four kinds of oral anaerobes in experimental group was better than that in control group. Further,the total clearance rate of the oral anaerobes was 72% in the experimental group and 49% in the control group,the difference was statistically significant as well( P < 0. 05). Conclusions: The concentrated tinidazole gargles in treatment of pericoronitis is superior to conventional method,and this treatment is worthy of clinical application.
关键词(KeyWords):
浓替硝唑含漱液;冠周炎;厌氧菌,口腔;疗效
concentrated tinidazole gargles;pericoronitis;anaerobes,oral;curative efficacy
基金项目(Foundation):
作者(Author):
侯豫
HOU Yu
DOI: 10.19367/j.cnki.1000-2707.2015.04.023
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