张嫩玲,叶道坤,田璧榕,吴林菁,张旭,龙庆德,沈祥春,张彦燕
ZHANG Nenling,YE Daokun,TIAN Birong,WU Linjing,ZHANG Xu,LONG Qingde,SHEN Xiangchun,ZHANG Yanyan

• 1:贵州医科大学药学院贵州省高等学校天然药物药理与成药性评价重点实验室
• 2:贵州医科大学天然药物资源优效利用重点实验室

摘要(Abstract)：

目的:研究天胡荽的化学成分。方法:采用硅胶柱色谱、Sephadex LH-20凝胶色谱MCI柱色谱及结晶、重结晶的方法进行分离纯化天胡荽各成,并运用波谱方法对所分得的化合物进行结构鉴定。结果:从天胡荽中分得了8个化合物,分别鉴定为槲皮素(quercetin)、芹菜素(apigenin)、山奈酚(kaempferol)、β-谷甾醇(β-sitosterol)、菠甾醇(α-spinasterol)、牡荆苷(vitexin)、异牡荆苷(isovitexin)以及胡萝卜苷(β-daucosterol)。结论:化合物5~7为首次从天胡荽中分离得到。
Objective: To study the chemical constituents of Hydrocotyle sibthorpioides. Methods:The constituents of Hydrocotyle sibthorpioides were separated by column chromatography,crystallization and recrystallization,and their structures were elucidated by spectroscophic means. Results: Eight compounds were isolated from the leaves of Hydrocotyle sibthorpioides and identified as quercetin( 1),apigenin( 2),kaempferol( 3),β-sitosterol( 4),α-spinasterol( 5),vitexin( 6),isovitexin( 7) and β-daucosterol( 8). Conclusion: Compounds 5-7 are obtained from Hydrocotyle sibthorpioides for the first time.

关键词(KeyWords)： 中草药;黄酮类;化合物;牡荆苷;异牡荆苷
Hydrocotyle sibthorpioides;flavonoids;chemical compound;vitexin;isovitexin

Abstract:

Keywords:

基金项目(Foundation): 教育部大学生创新训练计划项目(201610660024);; 贵州省卫生计生委科学技术基金(gzwjkj2014-2-103);; 贵州省科技厅-贵州医科大学联合基金[黔科合LH字(2015)7339]

作者(Author): 张嫩玲,叶道坤,田璧榕,吴林菁,张旭,龙庆德,沈祥春,张彦燕
ZHANG Nenling,YE Daokun,TIAN Birong,WU Linjing,ZHANG Xu,LONG Qingde,SHEN Xiangchun,ZHANG Yanyan

DOI: 10.19367/j.cnki.1000-2707.2017.10.007

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