肝康宁对病毒性肝炎血清脂质过氧化物的影响Therapeutic Observation of Gan-Kang-Ning in the Treatment of Virus Hepatitis
吴君,梁耀东,王荷菱
WU Jun 1; LIANG Yao dong 1; WANG He ling 2 (1.Department of Infectious;
摘要(Abstract):
目的 :探讨肝康宁治疗急、慢性病毒性肝炎的疗效。方法 :12 0例急、慢性肝炎住院及门诊患者 ,随机分为肝康宁治疗组和齐墩果酸治疗组 ,每日用药 3次 ,疗程 1~ 3个月。结果 :肝康宁对改善急、慢性肝炎患者的症状、体征及肝功能有明显效果 ,降酶、退黄作用亦明显。对血清白蛋白、球蛋白有一定的改善作用 ,且优于对照组 (P <0 .0 5 )。能降低血清丙二醛 (MDA)、肿瘤坏死因子 a(TNF a) ,升高红细胞超氧化物歧化酶 (SOD)活力 (P<0 .0 1)。结论 :肝康宁有保护肝细胞、降酶、退黄、调整蛋白、清除氧自由基及抗脂质过氧化的作用
Objective:To study the efficacy of Gan Kang Ning in the treatment of virus hepatitis. Methods: The 120 patients with acute and chronic virus hepatitis were divided into 2 groups (60 for each group). The experiment group was given Gan Kang Ning po, bid for 1~3 month and the control Oleanolic ocid. Results: Gan Kang Ning obviously improved the symptom, physical sign and the proportion of seum albumen, decrease serum levls of ALT, TBil, tumor necrosis factor a (TNF a), malondialdehyde(MDA), increase superoxide dismutase(SOD) in red blood cells (P<0.05). Conclusion: Gan睰ang Ning was effective in protecting hepatocytes, improving symptom, physical sign and the proportion of serum albumen, antioxidant properties and anti hepatic fibrosis.
关键词(KeyWords):
肝炎,病毒性,人;肝功能试验;肝康宁
hepatitis, viral, human; liver function tests; Gan Kang Ning
基金项目(Foundation):
作者(Authors):
吴君,梁耀东,王荷菱
WU Jun 1; LIANG Yao dong 1; WANG He ling 2 (1.Department of Infectious;
DOI: 10.19367/j.cnki.1000-2707.2001.05.015
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