王燕,周力,张永宏,张维,陈玉梅
WANG Yan 1; ZHOU Li 1; ZHANG Yong-hong 1; ZHANG Wei 2; CHEN Yu-mei 1 (1.Department of Digestive Internal Medicine;

• 1:贵阳医学院附院消化内科
• 2:贵阳医学院附院消化内科
• 3:贵阳医学院附院消化内科
• 4:贵阳医学院附院血液内科

摘要(Abstract)：

目的 :探讨肝硬化患者血清、腹水酸性α 醋酸萘酯酶 (ANAE)的含量与肝硬化肝功能Child pugh分级的关系。方法 :比色法测定肝硬化患者血清、腹水ANAE含量。结果 :肝硬化患者血清、腹水ANAE含量较对照组明显降低 ,其中肝硬化肝功能ChildB级以后血清、腹水ANAE含量下降明显。血清、腹水ANAE含量相关性显著。结论 :肝硬化患者血清、腹水ANAE含量 ,在一定程度上反映肝脏功能损害
Objective: To investigate the relationship between acid alpha naphthyl acetate esterase levels (ANAE) in serum and ascitic fluid of liver cirrhosis patients and Child’s grading of their liver function. Methods: α-ANAE levels in serum and ascite were measured with colorimetric assay. Results: α-ANAE levels in serum and ascite of liver cirrhosis patients were significantly lower than those of healthy controls (P<0.01). They correlated with the Child’s grading of liver function well. Conclusion: α-ANAE levels in serum and ascite of liver cirrhosis patients markedly decline and correlate with parameter of liver function. They may be useful in assessing the degree of liver damage.

关键词(KeyWords)： 肝硬化;腹水;血清;酸性α-醋酸萘酯酶;Child-pugh分级
liver cirrhosis; ascites; serum; acid alpha naphthyl acetate esterase; Child-pugh grading

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 王燕,周力,张永宏,张维,陈玉梅
WANG Yan 1; ZHOU Li 1; ZHANG Yong-hong 1; ZHANG Wei 2; CHEN Yu-mei 1 (1.Department of Digestive Internal Medicine;

DOI: 10.19367/j.cnki.1000-2707.2004.03.009

参考文献(References)：

• [1]赵景涛,刘玉兰.消化内科学[M].北京:中国协和医科大学出版社,2000.250.
• [2]周玉贵,王传芳,陆晓云,等.血清酸性α醋酸萘酯酶的比色测定及初步临床应用[J].临床检验杂志,2003,(4):211.
• [3]陈文彬.诊断学[M].北京:人民卫生出版社,2002.403.

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