骨髓增生异常综合征患者血清铁蛋白检测的意义Clinical Significance of Serum Ferritin Detection in Myelodysplastic Syndrome
葛韦,张瑞,杨忠文
GE Wei,ZHANG Rui,YANG Zhongwen
摘要(Abstract)：
目的:探讨血清铁蛋白(SF)检测对于骨髓增生异常综合征(MDS)的临床意义。方法:选取100例MDS患者,根据国际预后积分系统(IPSS)分级标准对患者进行危险度分级,并根据分级结果将患者分为低危组和高危组,选取健康人50例作为对照组,比较各组被检者SF水平及预后,分析两者的相关性。结果:MDS患者的SF水平均高于对照组(P<0.05),高危组患者的SF水平高于低危组(P<0.05),患者的不良预后与SF水平具有相关性(r=0.715,P<0.05)。结论:高危类型MDS患者的SF水平较高,患者的SF水平与其出现不良预后的机率具有相关性。
Objective: To investigate the clinical significance of serum ferritin( SF) detection in myelodysplastic syndrome( MDS). Methods: One hundred MDS patients were selected and divided into low risk group and high risk group according to IPSS scale of standard. 50 healthy adults were selected as the control group. The SF levels and prognosis of the included objects were detected and compared and then analyzing the correlation. Results: The SF level of the patients with MDS was significantly higher than that of the control group( P < 0. 05). The SF level of the patients with high risk group was significantly higher than that of low risk group. The poor prognosis of patients was correlated with the level of SF( r = 0. 715,P < 0. 05). Conclusion: The level of SF in MDS patients of high-risk group is higher. The SF level is correlated with poor prognosis in MDS patients.
关键词(KeyWords)：
骨髓增生异常综合征;血清;铁蛋白;预后
myelodysplastic syndromes;serum;ferritin;prognosis
基金项目(Foundation):
作者(Author):
葛韦,张瑞,杨忠文
GE Wei,ZHANG Rui,YANG Zhongwen
DOI: 10.19367/j.cnki.1000-2707.2015.09.028
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