杨媛;陈琛;冉利梅;杨星;闫雪秋;刘帝;
YANG Yuan;CHEN Chen;RAN Limei;YANG Xing;YAN Xueqiu;LIU Di;College of Public Health, Guizhou Medical University;Medical Examination Center,the Affiliated Hospital of Guizhou Medical University;College of Medicine and Health Management, Guizhou Medical University;

• 1:贵州医科大学公共卫生学院
• 2:贵州医科大学
• 3:贵州医科大学附院健康管理中心
• 4:贵州医科大学医药卫生管理学院

摘要(Abstract)：

目的:探讨围绝经期女性脑血管功能积分值与体质量指数(BMI)和血压水平的关系。方法:920例无卒中史的围绝经期女性,采用脑血管功能仪检测脑血管血流动力学指标、计算获取脑血管功能积分值,分为正常组(≥75分)和异常组(<75分),根据患者的BMI经患者分为体质量正常组、超重组和肥胖组,根据患者的血压水平将患者分为血压正常组、高血压1～3级(1、2、3级)组;比较异常脑血管功能积分值在不同年龄段的分布情况,分析围绝经期女性的BMI、血压水平与脑血管功能积分值的关系。结果:920名围绝经期女性中,脑血管功能积分值异常率为13.3%(122/920),且随年龄段的升高而升高,差异有统计学意义(χ■=23.283,P<0.01);体重正常组、超重组和肥胖组被检者的脑血管功能积分值异常率分别为8.8%、16.8%、38.5%,组间差异均具有统计学意义(P<0.01);血压正常组、一级高血压组、二级高血压组、三级高血压组被检者的脑血管功能积分值异常率分别为8.1%、48.1%、83.3%及100%,组间差异均有统计学意义(P<0.01)。结论:绝经期女性脑血管功能积分值与BMI和血压水平密切相关。
Objective: To investigate the association of brain vascular function scores with body mass index(BMI) and blood pressure levels of perimenopausal women. Methods: A total of 920 perimenopausal women without stroke history were enrolled. The cerebral vascular hemodynamics was detected by cerebrovascular function meter and the scores of cerebrovascular function were calculated to divide the enrollers into normal group(≥75 points) and abnormal group(<75). According to BMI, the enrollers were divided into the normal BMI group, overweight group and obese group. Based on blood pressure(BP) level, the enrollers were classified into the normal BP group and the high BP level 1 to 3(levels 1, 2, and 3). Abnormal cerebrovascular function scores was compared in different age groups. Moreover, the association between BMI and blood pressure level with cerebrovascular function scores was analyzed. Results: The abnormal rate of cerebrovascular function score was 13.3%(122/920), and it increased with age(χ~2_(trend)=23.283, P<0.01). The abnormal rates of cerebrovascular function scores were 8.8%, 16.8% and 38.5% in the normal weight, overweight and obesity groups, respectively(P<0.01). Moreover, the abnormal rates of cerebrovascular function scores were 8.1%, 48.1%, 83.3% and 100% in the normal group, the first-grade hypertension group, the second-grade hypertension group, and the third-grade hypertension group(P<0.01). Conclusion: The scores of cerebrovascular function in perimenopausal women are closely related to BMI and blood pressure levels.

关键词(KeyWords)： 围绝经期;卒中;血流动力学;脑血管功能;危险因素;因素分析
perimenopause;stroke;hemodynamics;cerebrovascular function;risk factor;factor analysis

Abstract:

Keywords:

基金项目(Foundation): 中国健康促进基金会(zhjkglqct2018-88-01)

作者(Author): 杨媛;陈琛;冉利梅;杨星;闫雪秋;刘帝;
YANG Yuan;CHEN Chen;RAN Limei;YANG Xing;YAN Xueqiu;LIU Di;College of Public Health, Guizhou Medical University;Medical Examination Center,the Affiliated Hospital of Guizhou Medical University;College of Medicine and Health Management, Guizhou Medical University;

Email:

DOI: 10.19367/j.cnki.1000-2707.2019.10.015

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