贵州医科大学学报

2018, v.43;No.212(05) 538-539+545

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大蝎子草地上部分化学成分研究
Chemical Constituents from the Aerial Parts of Girardinia diversifolia

张嫩玲;田婷婷;田璧榕;吴林菁;陶玲;沈祥春;
ZHANG Nenling;TIAN Tingting;TIAN Birong;WU Linjing;TAO Ling;SHEN Xiangchun;The High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability,Guizhou Medical University;The Union Key Laboratory of Guiyang City & Guizhou Medical University;

摘要(Abstract):

目的:研究大蝎子草地上部分的化学成分。方法:采用硅胶柱层析、Sephadex LH-20凝胶层析及MCI柱层析及结晶、重结晶方法分离纯化大蝎子草地上部分化合物,并运用波谱及化学方法对所分得的化合物进行结构鉴定。结果:从大蝎子草地上部分分离纯化得到5个化合物,经波谱解析鉴定为尿嘧啶、儿茶酚、5-硝基愈创木酚、β-谷甾醇及草酸,除化合物β-谷甾醇外均为首次从大蝎子草地上部分分离得到。结论:大蝎子草地上部分成分有尿嘧啶、儿茶酚、5-硝基愈创木酚、β-谷甾醇及草酸。
Objective: To study the chemical constituents from the aerial parts of Girardinia diversifolia. Methods: The constituents were isolated by column chromatography,and structures of the isolated compounds were identified by spectroscopic and chemical means. Results: Five compounds were isolated from the aerial parts of Girardinia diversifolia and identified as uracil,catechol,5-nitroguajacol,β-sitosterol and oxalic acid. Conclusions: All the compounds except β-sitosterol are extracted from Girardinia diversifolia for the first time.

关键词(KeyWords): 大蝎子草;荨麻科;层析法;化学成分;酚类;硅胶柱层析;凝胶层析
Girardinia diversifolia;Urticaceae;chromatography;chemical constituents;phenols silica gel column chromatography;gel chromatography

Abstract:

Keywords:

基金项目(Foundation): 贵州省卫生计生委科学技术基金项目(gzwjkj2014-2-103);; 贵州省科技厅-贵州医科大学联合基金项目[黔科合LH字(2015)7339]

作者(Author): 张嫩玲;田婷婷;田璧榕;吴林菁;陶玲;沈祥春;
ZHANG Nenling;TIAN Tingting;TIAN Birong;WU Linjing;TAO Ling;SHEN Xiangchun;The High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability,Guizhou Medical University;The Union Key Laboratory of Guiyang City & Guizhou Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2018.05.009

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