贵州医科大学学报

2002, (03) 214-216

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166例乳腺癌术后辅助治疗远期疗效分析
The Long-term Treating Results of Postoperative Adjuvant Therapy to 166 Patients with Breast Cancer

董洪敏,王文玲,文小平
DONG Hong min, WANG Wen ling, WEN Xiao ping (Department of Oncology, The Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China)

摘要(Abstract):

目的 :探讨乳腺癌根治术后辅助治疗的远期疗效。方法 :16 6例乳腺癌病人 (Ⅱ期 90例 ,Ⅲ期 76例 )均行根治性手术治疗 ,术后分别采用单纯放疗、单纯化疗及化疗加放疗等辅助治疗。结果 :Ⅱ期和Ⅲ期乳腺癌患者 10年生存率分别为 5 1 1% (46 / 90 )、2 2 4 % (17/ 76 )。术后放疗组、术后放疗加化疗局部复发率 (局部及区域淋巴结复发 )均低于术后单纯化疗组 (P <0 0 5 ) ;术后化疗组及术后放疗加化疗组远处转移率均低于术后单纯放疗组 (P <0 0 5 ) ;术后放疗加化疗组 10年生存率较术后单纯化疗及单纯放疗组明显提高 (P <0 0 5 )。结论 :Ⅱ、Ⅲ期乳腺癌术后辅助放疗可以减少局部复发率 ,术后化疗可以减少远处转移率 ,术后放疗加化疗可以明显提高 10年生存率
Objective:To analyse the treating results of postoperative adjuvant therapy to 166 patients with breast cancer.Methods:Treatment results of 166 patients in our department from May 1985 to May 1991 were analysed.Comparision were made among patients of stage Ⅱ(90 cases)and stage Ⅲ(76 cases) patients received postoperative radiotherapy(RT),chemotherapy(CT),and chemotherapy plus radiotherapy(CRT).Results:The 10 year survival rates of patients of stage Ⅱ and stage Ⅲ were 51 1%(46/90)and 22 4%(17/76)respectively.When they received CRT therapy,the local recurrence rates of stage Ⅱ and stage Ⅲpatients of RT,CRT,and CT groups differed sigeificantly(P<0 05).The distant metastasis of stage Ⅱ and stage Ⅲ patients of RT and CRT groups were different from that of RT group(P<0 05).Conclusion:Postoperative adjuvant therapy could reduce the local recurrence rates and distant metastasis rates and increase 10 year survival rates.

关键词(KeyWords): 乳房切除术,根治性;复发;肿瘤转移;放射疗法;药物疗法
mastectomy,radical; recurrence; neoplasm metastasis; radiotherapy; drug therapy

Abstract:

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作者(Author): 董洪敏,王文玲,文小平
DONG Hong min, WANG Wen ling, WEN Xiao ping (Department of Oncology, The Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China)

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DOI: 10.19367/j.cnki.1000-2707.2002.03.010

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