贵州医科大学学报

2015, v.40;No.176(05) 539-541

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12例重症多形红斑型药疹临床分析
Clinical Analysis on 12 Cases of Severe Erythema Multiforme Drug Eruption

王江涛;
WANG Jiangtao;Department of Dermatology,People's Hospital of Nanhai Economic Development Zone;

摘要(Abstract):

目的:探讨重症多形红斑型药疹的临床特点、治疗及预后。方法:分析12例重症多形红斑型药疹患者的致敏药物、临床表现,观察治疗疗效及预后。结果:12例患者中,有11例可以确定致敏药物,主要是解热镇痛药,其次为抗生素;11例患者用糖皮质激素治疗症状控制良好,1例患者加用免疫球蛋白,12例患者全部治愈。结论:重症药疹应早期、足量应用糖皮质激素治疗,必要时应用免疫球蛋白。
Objective: To analyze the clinical features,treatment and prognosis of severe erythema multiforme drug eruption. Methods: Allergenic drugs,clinical features,treatment and prognosis of twelve severe erythema multiforme drug eruption patients were analyzed. Results: Eleven cases were confirmed to be caused by one drug,and mainly antipyretic analgesics,followed by Antibiotics. 11 patients were treated with glucocorticoid,and the symptom was well controlled,one patient added immunoglobulin,all the cases were cured. Conclusion: It is important to give sufficient glucocorticoid earlier in the treatment of severe drug eruption,and use immunoglobulin when necessary.

关键词(KeyWords): 药疹;药物过敏;糖皮质激素类;免疫球蛋白类
drug eruption;drug hypersensitivity;glucocorticoids;immunoglobulins

Abstract:

Keywords:

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作者(Author): 王江涛;
WANG Jiangtao;Department of Dermatology,People's Hospital of Nanhai Economic Development Zone;

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DOI: 10.19367/j.cnki.1000-2707.2015.05.032

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