赵丹青,袁航,李立,杨菲,朱玉花,胡琴,梁一
ZHAO Danqing,YUAN Hang,LI Li,YANG Fei,ZHU Yuhua,HU Qin,LIANG Yi

• 1:贵州医科大学附属医院妇产科
• 2:贵州医科大学附属医院检验科
• 3:贵州医科大学附属医院营养科

摘要(Abstract)：

目的:初步建立不同孕期孕妇血液白细胞参数的参考区间。方法:采用整群随机抽样方法,抽取常规产检符合条件的孕妇8 275名,分为早孕期(6～13周末)、中孕期(14～27周末)及晚孕期(28～41周) 3组,调取血常规白细胞检测结果,使用SAS9.3进行数据分析并确定医学参考值范围,比较各孕期各类白细胞的参考区间的差别及与非孕正常成人标准的差别。结果:采用95%的参考区间(P_(2.5)～P_(97.5))成功获得各孕期各类白细胞的参考区间,该参数区间不同于非孕正常成人标准,经Kruskal-Wallis H秩和检验比较,该参考区间在早、中、晚3个孕期组间比较,差异有统计学意义(P <0.05)。结论:本次确立的不同孕期白细胞参数参考区间不同于非孕正常成人标准,不同孕周的各类白细胞参数也有所不同。
Objective: To establish the parameter intervals of leukocytes in different stages of pregnancy. Methods: A total of 8 275 pregnant women underwent routine pregnancy care and qualified for the study were chosen by using the cluster random sampling method. They were divided into early( 6 ～ 13 weeks),middle( 14 ～ 27 weeks) and late( 28 ～ 41 weeks) pregnancy groups. The results of blood routine on leukocytes test were collected and the data was analyzed by SAS9. 3 to determine the medical parameter interval. Such analysis would be used to compare the differences between leukocytes parameter intervals indifferent pregnancy stages,as well as the differences between pregnant women and non-pregnant health adults. Results: 95% parameter interval( P_(2. 5)～ P_(97. 5)) was used to determine the range of medical parameter intervals of white cell in different pregnant stages.This parameter interval is different from that of non-pregnant adults ' standard. By Kruskal-Wallis H rank sum test,the differences of all leukocytes parameters among the three groups were statistically significant( P < 0. 05). Conclusion: The leukocytes parameter interval range of different pregnant stages established in this study is different from non-pregnant adults,so is the various leukocytes parameters of different pregnant stages.

关键词(KeyWords)： 妊娠;白细胞;淋巴细胞;中性粒细胞;生物参考区间;绝对值
pregnancy;leukocytes;lymphocytes;neutrophils;biological parameter intervals;absolute value

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(8196028);; 贵州省科学技术厅基金[黔科合(2020)1Y308]

作者(Author): 赵丹青,袁航,李立,杨菲,朱玉花,胡琴,梁一
ZHAO Danqing,YUAN Hang,LI Li,YANG Fei,ZHU Yuhua,HU Qin,LIANG Yi

DOI: 10.19367/j.cnki.2096-8388.2020.10.012

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