贵州医科大学学报

2009, v.34;No.137(02) 173-174+177

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

妊娠高血压孕妇血浆D二聚体含量与血液流变学的相关性研究
The Relationship of Plasma D-dimers and Hemorheology in Patients with Pregnancy Induced Hypertension

袁筑华;袁凤琼;陈淼鑫;付原;
YUAN Zhuhua1,YUAN Fengqiong2,CHEN Miaoxin1,FU Yuan3(1.Department of Obstetric and Gynecology,The Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China;2.Health Agency of Maternal and Child,Center for Disease Control of Guizhou Province,Guiyang 550001,Guizhou,China;3.The Central Laboratory,The Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China)

摘要(Abstract):

目的:探讨妊娠高血压孕妇血浆D二聚体(DD)与血液流变学的相关关系。方法:采用ELISA双抗体夹心法检测正常妊娠和妊高征孕妇血浆D二聚体含量,并与其血液流变学参数红细胞压积(HCT),全血黏度(WBV),血浆黏度(PV),血沉(ESR)进行相关性分析。结果:妊高征组血浆D二聚体水平明显高于正常妊娠组(P<0.01);妊高征组血浆D二聚体水平与红细胞压积、全血黏滞度呈显著正相关(P<0.01),与血沉、血浆黏度无明显相关性(P>0.05);正常妊娠组与这四项指标无明显相关性(P>0.05)。结论:D二聚体参与了妊高征的发病过程,随着病情的加重逐渐升高,并与其血液黏滞度增高的变化相关。
Objective: To study the relationship of plasma D-dimers(DD) with hemorheology in patients with pregnancy induced hypertension(PIH).Methods: A total of 60 persons were chosen as research subjects.Of them,30 were PIH patients,and the other 30 were normal pregnant women as controls.Plasma levels of DD were measured with enzyme-linked immunosordent assays(ELISA).Hemorheological parameters of hematocrit(HCT),whole blood viscosity(WBV),plasma viscosity(PV) and erythrocyte sedimentation rate(ESR) were tested,and the data were statistically analyzed,specially for the correlation between DD and these parameters.Results: Plasma DD levels of PIH patients were higher than those of normal control(P<0.01).In PIH group,the plasma DD levels positively correlated with HCT and WBV,but did not correlate with PV or ESR.In control group,the plasma DD levels did not correlate with these hemorheological parameters.Conclusions: Plasma DD might participate the development of PIH and increase gradually along with the aggravation of the disease,and its increase correlates with the raise of WBV.

关键词(KeyWords): 妊娠;妊娠中毒症,EPH;D二聚体;血液流变学
pregnancy;gestosis,EPH;D-dimers;haemorheology

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 袁筑华;袁凤琼;陈淼鑫;付原;
YUAN Zhuhua1,YUAN Fengqiong2,CHEN Miaoxin1,FU Yuan3(1.Department of Obstetric and Gynecology,The Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China;2.Health Agency of Maternal and Child,Center for Disease Control of Guizhou Province,Guiyang 550001,Guizhou,China;3.The Central Laboratory,The Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China)

Email:

DOI: 10.19367/j.cnki.1000-2707.2009.02.017

文章评论(Comment):

序号(No.) 时间(Time) 反馈人(User) 邮箱(Email) 标题(Title) 内容(Content)
反馈人(User) 邮箱地址(Email)
反馈标题(Title)
反馈内容(Content)
扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享