万秀方,张亚莉

• 1:贵州医科大学医学检验学院血液学教研室

摘要(Abstract)：

<正>机体细胞内DNA会受到多种因素的影响,导致其化学结构或编码特性的改变,如电离辐射、化学物质、异常代谢产物等都会导致DNA损伤,这种损伤若不能及时得到修复,就会影响机体正常活动,进而诱发一系列遗传疾病的产生。正常机体具有完善的DNA损伤修复机制,修复由各种原因导致的DNA损伤,其主要机制有两种:一种是损伤恢复(reversal of damage),即损伤直接被移除,使碱基

关键词(KeyWords)： DNA损伤;DNA甲基化;DNA修复;肿瘤

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(No.81360437)

作者(Author): 万秀方,张亚莉

DOI: 10.19367/j.cnki.1000-2707.2015.06.001

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