何红月
HE Hongyue

• 1:海南省妇幼保健院药剂科

摘要(Abstract)：

目的:观察开喉剑喷雾剂治疗儿童急性咽喉炎的临床疗效。方法:确诊急性咽喉炎患儿160例,均分为开喉剑喷雾剂组与咽扁冲剂组,分别给予口服开喉剑喷雾剂、咽扁冲剂治疗,比较一个疗程后两组患者的总有效率、症状消失时间及不良反应。结果:开喉剑喷雾组总有效率(95.00%)高于咽扁冲剂组(80.00%)(χ~2=4.37,P<0.05),咽部干燥、灼热,声音嘶哑,食欲不振消失时间短于咽扁冲剂组,差异有统计学意义(t=3.24、3.56、4.01,P<0.05);不良反应发生率(7.50%)低于咽扁冲剂组(10.00%)(χ~2=2.55,P<0.05)。结论:采用开喉剑喷雾剂治疗儿童急性咽喉炎的临床疗效优于咽扁冲剂。
Objective: To investigate the clinical efficacy of Kaihoujian Spray in treating the children with acute laryngopharyngitis. Methods: 160 children with acute laryngopharyngitis were divided with equal number into Kaihoujian Spray group and Yanbian Electuary group. The clinical curative effect,symptom disappearance time and the adverse reactions of patients in the two groups were compared after treated according for one treatment stage. Results: The total effective rate of patients in Kaihoujian Spray was 95. 00%,higher than 80. 00% in Yanbian Electuary( χ~2= 4. 37,P < 0. 05). In Kaihoujian Spray group,the disappearance time of throat dry,heat,voice hoarse and anorexia was shorter than that of Yanbian Electuary group,the differences were statistical significant( t = 3. 24、3. 56、4. 01,P <0. 05). The adverse reaction rate of Kaihoujian Spray group was 7. 50% lower than that of 10. 00% in Yanbian Electuary group( χ~2= 2. 55,P > 0. 05). Conclusion: The curative effect of Kaihoujian Spray in treating the children with acute laryngopharyngitis is significant.

关键词(KeyWords)： 咽喉疾病;急性病;儿童;疗效,开喉剑喷雾剂
pharyngolaryngeal diseases;acute disease;child;curative effect;Kaihoujian spray

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 何红月
HE Hongyue

DOI: 10.19367/j.cnki.1000-2707.2016.05.032

参考文献(References)：

• [1]Kawamata S,Yamada H,Sato Y,et al.Evaluation of the safety and efficacy of cefditoren pivoxil fine granules for pediatric use in pediatric patients with laryngopharyngitis and tonsillitis caused by Streptococcus pyogenes[J].Jpn J Antibiot,2010(4):299-311.
• [2]张丽.92例雾化吸入治疗小儿急性咽喉炎的临床护理[J].医药前沿,2012(20):241.
• [3]林文.开喉剑喷雾剂治疗小儿上呼吸道急性化脓性扁桃体炎80例[J].现代远程教育,2013(11):90-91.
• [4]王晓瑜,辜艳.开喉剑喷雾剂治疗疱疹性咽峡炎疗效观察[J].中国现代药物应用,2011(14):23-24.
• [5]胡亚美,江载芳.诸福棠实用儿科学[M].7版.北京:人民卫生出版社,2005:807-808.
• [6]周慧.开喉剑喷雾剂治疗儿童急性喉炎的有效性和安全性评价[J].现代医药卫生,2013(11):1645-1646.
• [7]邓红,张丽霞.中西医结合治疗小儿化脓性扁桃体炎疗效分析[J].实用临床医学,2011(8):85-86.
• [8]解桂清.甲硝唑联合青霉素治疗急性扁桃体炎临床疗效观察[J].基层医学论坛,2012(8):996-997.
• [9]顾军养,韩薇.盐酸肾上腺素联合布地奈德雾化吸入辅助治疗小儿喉炎30例[J].医药导报,2010(2):202-203.
• [10]Rrenzi PM,Turgeon JP,Marcohe JE.Reduced interferon-gamma production in infants with bronchiolitis and asthma[J].American Journal of Respiratory and Critical Care Medicine,2011(6):890-891.
• [11]Kimpen JL.Schad UB Treatment of respiratory syncytial virus bronchiolitis:1995 poll of members of the European Society for Paediatric Infectious Diseases[J].Pediatric Infectious Disease Journal,2012(5):56-57.
• [12]王玉香,庞来祥,范亮.清咽亮嗓口服液治疗急性咽炎、扁桃体炎127例[J].陕西中医学院学报,2011(1):90-91.
• [13]Zhang X,Patel A,Horibe H,et al.Cholesterol,coronary heart disease heart disease,and stroke in the Asia Pacific region[J].Int J Epidemiol,2013(4):562-564.

文章评论(Comment)：