廖玮玮,何志旭,冉立
LIAO Weiwei,HE Zhixu,RANli

• 1:贵州医科大学
• 2:贵州省肿瘤医院

摘要(Abstract)：

目的:分析不同性别和年龄的儿童实体瘤的肿瘤种类构成差异,为临床儿童实体瘤的早期诊断和选择治疗方案提供依据。方法:选取住院治疗的年龄≤14岁、经病理确诊为实体瘤且有完整病例资料的1 147例患儿,分析实体瘤患儿的年龄分布、不同病理类型实体瘤患儿的性别构成同时分析淋巴瘤、肾母细胞瘤及神经母细胞瘤3种常见的小儿恶性实体瘤病理分期及临床表现。结果:1 147例实体瘤患儿中,男性发病多于女性(1.17∶1),良性发病多于恶性(2.81∶1);良性发病年龄呈双高峰趋势,恶性发病年龄呈单一高峰趋势,多因发现局部包块就诊;良性实体瘤中,血管瘤、良性囊肿及淋巴管瘤最常见,恶性实体瘤中,淋巴瘤、神经母细胞瘤、肾母细胞瘤及生殖细胞肿瘤最多见;恶性实体瘤初诊时多为中晚期,淋巴瘤及上皮源性肿瘤(肝细胞肝癌、甲状腺癌)学龄期发病多见,胚胎源性肿瘤(神经母细胞瘤、肾母细胞瘤、生殖细胞肿瘤)婴幼儿期发病多见。结论:不同年龄和性别的儿童实体瘤构成比有差异,其发病特点及生物学特性有自身独特的特点。
Objective: Analyzing the clinical data of children with solid tumors,to summarize the differences of gender and age in the composition of tumor,to provide reliable data for early diagnosis and treatment for solid tumors in children. Methods: To analyze 1147 patients diagnosed as solid tumors confirmed by pathological examination,aged ≤ 14 years old. Analyzing patients' age distribution,gender composition of different pathological solid tumor patients,analyzing pathological staging and clinical manifestation of lymphoma,nephroblastoma and neuroblastoma. Results: 1147 cases of solid tumors,there were more male patients than female ones( 1. 17∶ 1). There were more benign solid tumors than malignant solid tumors( 2. 81∶ 1); The age of benign solid tumors onset was double peaked,the age of malignant solid tumors onset showed a single peak trend,. The primary clinical symptoms of solid tumors were mainly about localized occurred mass. For benign solid tumors,hemangioma,benign cyst and lymphangioma were the most common ones. For malignant solid tumors,lymphoma,neuroblastoma,nephroblastoma and germ cell tumors were most common ones. The most common malignant solid tumors were diagnosed as advanced stage. Lymphoma and epithelial tumors( hepatocellular carcinoma and thyroid carcinoma) are more common in school age; embryonal tumors( neuroblastoma,nephroblastoma and germ cell tumors) are more common in infant stage. Conclusion: There are differences in solid tumor types in terms of ages and genders; solid tumors of children have their own unique characteristics.

关键词(KeyWords)： 实体瘤,儿童;性别;年龄;构成比;肿瘤
solid tumors,children;age;gender;composition rate;tumor

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 廖玮玮,何志旭,冉立
LIAO Weiwei,HE Zhixu,RANli

DOI: 10.19367/j.cnki.1000-2707.2017.10.027

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