张爱华，蒋宪瑶，龙曼海，谢亚雄，蒙顺松，程学方，段和平，杨银霞
zhang Aihua et al (Department of Publec Health;

• 1:贵阳医学院卫生系，贵州省某汞矿医院

摘要(Abstract)：

报道了６０例金属汞密切接触工人的外周血淋巴细胞微核率（ＭＮ）和姐妹染色单体互换率（ＳＣＥ）的观察分析。结果表明各工龄组姐妹染色单体互换率均明显高于对照组（Ｐ＜０．０５），微核率则接触工龄１０年以上组有统计学意义。同时分析了尿汞与汞诱变作用的关系及吸烟对汞诱变作用的影响。
The frequencies of micronucleus and sister chromatid exchange in peripheral blood lymphocytes of 60 workers closely exposed to mercury were analysed. The workers of 2-27 working year were divided into 4 groups. As a result, the sister chromatid exchange frequencies in all working-year groups(i.e. 4.91, 4.99, 5.13/cell) were obviously higher than those in the control group (4.23/cell), and the differences were significant(P<0.05).The ftequencies of lymphocyte micronucleus in the over-10-working-year group and the over-20-working-year group were 2.82 and 2.97% respectively and were both obviously higher than those in the control group (1.59%), and the differences were also significant (P<0.01).But the differences between the control group and the other 2 groups (i.e. the group of under-10-working-year) were insignificant.The relationship between urine mercury and the mutagenic effect of mercury was analysed, and the influence of cigarette smoking the mutagenic effect of mercury was also analysed.

关键词(KeyWords)： 汞中毒，姐妹染色单体交换，遗传学，微核
mercury poisoning; sister chromatid exchange; genetics; micronucleus

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 张爱华，蒋宪瑶，龙曼海，谢亚雄，蒙顺松，程学方，段和平，杨银霞
zhang Aihua et al (Department of Publec Health;

DOI: 10.19367/j.cnki.1000-2707.1994.02.005

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