贵州医科大学学报

1989, (04) 277-281

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100例胆道感染的免疫学探索——胆汁培养与血清、胆汁、胆囊组识匀浆Ig检测
A Preliminary Immunological Investigation in Patients with Biliary Tract Infection

夏亮芳;王福华;潘揚;胡康;李昆;祝家乃;王伟;
Xia Liangfang, et al Department of Sugery

摘要(Abstract):

收集100例术中胆囊或胆管胆汁进行细菌培养、测免疫球蛋白(Ig)含量,并测血清Ig含量,及34例胆囊组织匀浆Ig含量。结果表明胆道感染患者血清中三类Ig含量极显著高于正常人(n=100,P<0.01)。胆汁培养阳性组血清IgA显著高于阴性组(P<0.01)。胆汁培养单一菌种生长时血清IgA高于2种以上细菌生长,其余Ig含量在胆汁培养1~3种细菌生长,或草兰氏阴性杆菌或阳性球菌时差异均无显著性(P>0.05),胆汁培养阳性组胆囊汁中IgG高于胆管胆汁;阴性组胆管胆汁中IgG高于胆囊胆汁。胆囊胆汁培养阳性组胆囊胆汁中三类Ig含量均高于胆囊组织匀浆;阴性组其IgG和IgM高于胆囊组织匀浆,而IgA无明显相关关系。
The results of bacterial culture of the bile collected from both the bile cyst and duct during operation and the determinations of IgG, IgA and IgM of the serum and bile in 100 cases of biliary tract infection are reported, The contents of Ig of the bile cyst tissue homolization were determined in 34 out of the above mentioned 100 cases, We discover that the contents of all the three kinds Ig in patients are sig- nificantly higher than normal subjects (P<0. 01).The quantities of serum IgA in patients with positive bacterial culture are higher significantly than patients with negative culture (P<0. 01), There are no differences in contents of all three kinds Ig between patients with positive culture(P>0. 05). The quantities of cystic bile IgG in cultural positive patients are higher than duct bile IgG, but the conditions are just inversely in cultural negative patients (P<0. 05). The contents of cystic bile IgG, IgA and IgM in cultural positive patients are higher than the Ig contents in cystic tissue homolization. The quantities of cystic bile IgG and IgM are higher than that in the cystic tissue homolization, but there are no differnces in the contents if IgA between cystic bile and tis- sue homolization in the cultural negative group.

关键词(KeyWords): 免疫测定;感染;免疫球蛋白;胆汁;胆囊;胆管;组织提取物
immunoassay; infeetion; immunoglobulin; blie; cystic; duct; tissue extracts

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作者(Author): 夏亮芳;王福华;潘揚;胡康;李昆;祝家乃;王伟;
Xia Liangfang, et al Department of Sugery

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DOI: 10.19367/j.cnki.1000-2707.1989.04.009

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