贵州医科大学学报

1999, (01) 3-5

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抗氧化中药治疗工业性氟病
Clinical Efficacy of Anti oxidation Preparation of Traditional Chinese Medicine in the Treatment of Industral Fluorosis

王毅,甘嘉琪,王伟,邵亚萍,赵燕,赵明祥
Wang Yi, et al. Aluminium Factory Workers, Hospital of Guizhou

摘要(Abstract):

0例工业性氟病患者连续服用抗氧化中药(绞股蓝-丹参复方制剂)1年,尿氟排泄量逐月增加,于3个月达高峰,并维持于较高水平至服药结束,具有显著性差异(P<0005);头发和指甲氟含量明显减少(P<0005);超氧化物歧化酶(SOD)活性增加(P<001);丙二醛(MDA)含量减少(P<005)。骨X线片显示部分骨密度减低,骨X线片好转率1364%。服药后患者感骨关节疼痛减轻。服药期间未发现不良反应。
Sixty cases of patients of industrial fluorosis were treated with anti-oxidation preparation of traditional Chinese medicine for one year.It is found that fluoride concentration in urine of the patients gradually increased, and reached a high peak from three-months of the treatment and remained until the treatment finished. There was specially significant difference between before and after the treatment (P<0 005),fluroide concentration in hair and nail of the patients marked decreased, superoxide dismutase(SOD)activity in red blood cell increased and malonaldehyde(MDA) concentration in blood plasma decreased. X-rays showed that density of bone decreased,pain in bone and joint of the patients eased after the treatment, side effect was not observed during study.

关键词(KeyWords): 氟化物中毒,超氧化物歧化酶,丙二醛,抗氧化中药
fluoride poisoning; superoxide dismutase;malondialdehyde;traditional Chinese medicine of anti-oxidation

Abstract:

Keywords:

基金项目(Foundation): 卫生部科研基金

作者(Author): 王毅,甘嘉琪,王伟,邵亚萍,赵燕,赵明祥
Wang Yi, et al. Aluminium Factory Workers, Hospital of Guizhou

Email:

DOI: 10.19367/j.cnki.1000-2707.1999.01.006

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