杜琎,杨丹宁,胡定辉,李航,刘尊涛,邢雪梅
DU Jin,YANG Danning,HU Dinghui,LI Hang,LIU Zuntao,XING Xuemei

• 1:南京中医药大学附属中西医结合医院心胸外科

摘要(Abstract)：

目的:探讨医用聚氨基葡萄糖羧酸钠生物胶体液在胸外科手术中的应用效果。方法:将100例胸部手术患者随机均分为观察组和对照组,观察组在手术结束关闭胸腔前应用医用聚氨基葡萄糖羧酸钠生物胶体液冲洗胸腔,对照组应用生理盐水冲洗胸腔;比较两组患者术后3 d的胸腔引流量、胸管留置时间、住院时间、发热情况、切口愈合情况以及白细胞计数(WBC)、C-反应蛋白(CRP)、血清降钙素原(PCT)水平。结果:观察组病例术后3 d的胸腔引流量、胸管留置时间、住院时间均少于对照组,两组差异具有统计学意义(P<0.05);观察组术后WBC、CRP、PCT均显著低于对照组,差异有统计学意义(P<0.05)。结论:聚氨基葡萄糖羧酸钠生物胶体液能够明显减少胸外科手术后渗出,预防胸腔积液,减轻炎症反应。
Objective: discuss the efficacy of glucosamine carboxylic acid sodium biological colloid liquid in thoracic surgery. Methods: 100 patients who had received thoracic surgery were randomly divided into observation group,in which glucosamine carboxylic acid sodium biological colloid liquid was used to wash the thoracic cavity before closing it,and control group,in which physiological saline was used to wash the thoracic cavity. Three days after surgery,thoracic drainage volume,thoracic catheter detaining duration,length of stay,fever,incision healing status,white blood cell( WBC) count as well as levels of C-reactive protein( CRP) and serum procalcitonin( PCT) were compared between the two groups. Results: Three days after surgery,the thoracic drainage volume,thoracic catheter detaining duration and length of stay were lesser or shorter in the observation group than those in the control group,and the difference was statistically significant( P < 0. 05). The levels of WBC,C-reactive protein and serum procalcitonin were significantly lower in the observation group than their counterparts in the control group,and the difference was statistically significant( P < 0. 05). Conclusion: Glucosamine carboxylic acid sodium biological colloid liquid can significantly reduce post-operative exudation,prevent pleural effusion and alleviate inflammatory reaction in thoracic surgery.

关键词(KeyWords)： 胸外科手术;白细胞计数;C-反应蛋白;降钙素原;治疗效果
glucosamine carboxylic acid sodium biological colloid liquid;thoracic surgical procedures;leukocyte count;C reactive protein;procalcitonin;curative effect

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 杜琎,杨丹宁,胡定辉,李航,刘尊涛,邢雪梅
DU Jin,YANG Danning,HU Dinghui,LI Hang,LIU Zuntao,XING Xuemei

DOI: 10.19367/j.cnki.1000-2707.2017.04.022

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