贵州医科大学学报

1990, (01) 29-32

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古尼拟青霉药理作用研究 2.抗炎作用及对免疫过程的影响
Study of the Pharmacologic Action of Paecilomyces Gunnii Ⅱ.The anti-inflammatory effect and the influence on immunologic process

鲍淑娟;李淑芳;韩君勇;韩国强;
Bao Shujuan, et al Department of Pharmacology

摘要(Abstract):

本文报道古尼拟青霉(paecilomyces gunnii)的抗炎作用及对免疫过程的作用。结果表明:古尼拟青霉能明显地抑制小鼠背部皮肤、耳廓及腹腔毛细血管通透性,对大鼠后足(左右)蛋清性肿胀及大鼠肉芽组织增生均有抑制作用;对大鼠、小鼠被动皮肤过敏反应(PCA)及小鼠主动皮肤过敏反应(ACA)均有抑制作用。
A study of the anti-inflammatory effect and the influence on immunologic process of paecilomyces gunnii is reported.The results of experiments indicated that paecilomyces gunnii can inhibit markedly: capillary permeability in dorsal skin, auricle, abdominal cavity of mice at the acute inflammatory stags; the egg white-induced swelling in feet of rats; the granulation tissue hyperplasia in skin incision of rats at the eighth day; the passive cutaneous anaphylaxis in rats and mices; the active cutaneous anaphylaxis in mices.

关键词(KeyWords): 古尼拟青霉;被动皮肤过敏性;主动皮肤过敏性;毛细血管通透性;小鼠;大鼠
paecilomyces gunnii;passive cutaneous anaphylaxis;active cutaneous anaphylaxis;capillaly permeability;mice;rats

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 鲍淑娟;李淑芳;韩君勇;韩国强;
Bao Shujuan, et al Department of Pharmacology

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DOI: 10.19367/j.cnki.1000-2707.1990.01.009

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